| Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies G Codolo, N Plotegher, T Pozzobon, M Brucale, I Tessari, L Bubacco, ... PloS one 8 (1), e55375, 2013 | 503 | 2013 |
| Impaired dopamine metabolism in Parkinson’s disease pathogenesis A Masato, N Plotegher, D Boassa, L Bubacco Molecular neurodegeneration 14 (1), 1-21, 2019 | 179 | 2019 |
| DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function N Plotegher, G Berti, E Ferrari, I Tessari, M Zanetti, L Lunelli, E Greggio, ... Scientific reports 7 (1), 40699, 2017 | 117 | 2017 |
| Mitochondrial dysfunction and neurodegeneration in lysosomal storage disorders N Plotegher, MR Duchen Trends in molecular medicine 23 (2), 116-134, 2017 | 115 | 2017 |
| Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells. GE Russo Isabella, Berti Giulia, Plotegher Nicoletta, Bernardo Greta ... J Neuroinflammation 12 (1), 230, 2015 | 108* | 2015 |
| Alpha-synuclein pore forming activity upon membrane association L Tosatto, AO Andrighetti, N Plotegher, V Antonini, I Tessari, L Ricci, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (11), 2876-2883, 2012 | 101 | 2012 |
| LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate. GE Belluzzi E, Gonnelli A, Cirnaru MD, Marte A, Plotegher N, Russo I ... Molecular Neurodegeneration 11 (1), 1, 2016 | 90 | 2016 |
| Crosstalk between lysosomes and mitochondria in Parkinson's disease N Plotegher, MR Duchen Frontiers in cell and developmental biology 5, 110, 2017 | 88 | 2017 |
| Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells N Plotegher, E Gratton, L Bubacco Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (6), 2014 | 88 | 2014 |
| The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity N Plotegher, D Kumar, I Tessari, M Brucale, F Munari, L Tosatto, ... Human molecular genetics 23 (21), 5615-5629, 2014 | 61 | 2014 |
| LRRK2 deficiency impacts ceramide metabolism in brain R Ferrazza, S Cogo, H Melrose, L Bubacco, E Greggio, G Guella, ... Biochemical and biophysical research communications 478 (3), 1141-1146, 2016 | 58 | 2016 |
| Ceramides in Parkinson’s disease: from recent evidence to new hypotheses N Plotegher, L Bubacco, E Greggio, L Civiero Frontiers in Neuroscience 13, 330, 2019 | 51 | 2019 |
| Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity N Plotegher, E Greggio, M Bisaglia, L Bubacco Quarterly reviews of biophysics 47 (1), 1-48, 2014 | 48 | 2014 |
| Lysines, Achilles’ heel in alpha-synuclein conversion to a deadly neuronal endotoxin N Plotegher, L Bubacco Ageing research reviews 26, 62-71, 2016 | 39 | 2016 |
| Parkinson’s disease–associated LRRK2 interferes with astrocyte-mediated alpha-synuclein clearance L Streubel-Gallasch, V Giusti, M Sandre, I Tessari, N Plotegher, E Giusto, ... Molecular Neurobiology 58, 3119-3140, 2021 | 38 | 2021 |
| NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells N Plotegher, C Stringari, S Jahid, M Veronesi, S Girotto, E Gratton, ... The FASEB Journal 29 (6), 2484, 2015 | 31 | 2015 |
| Divergent effects of G2019S and R1441C LRRK2 mutations on LRRK2 and Rab10 phosphorylations in mouse tissues L Iannotta, A Biosa, JH Kluss, G Tombesi, A Kaganovich, S Cogo, ... Cells 9 (11), 2344, 2020 | 30 | 2020 |
| Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload N Plotegher, D Perocheau, R Ferrazza, G Massaro, G Bhosale, F Zambon, ... Cell Death & Differentiation 27 (5), 1588-1603, 2020 | 26 | 2020 |
| Excitotoxicity revisited: Mitochondria on the verge of a nervous breakdown N Plotegher, R Filadi, P Pizzo, MR Duchen Trends in Neurosciences 44 (5), 342-351, 2021 | 24 | 2021 |
| High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy F Piccirilli, N Plotegher, MG Ortore, I Tessari, M Brucale, F Spinozzi, ... Biophysical journal 113 (8), 1685-1696, 2017 | 19 | 2017 |
Luigi BubaccoDipartimento di Biologia , Università degli Studi di Padova, ItalyVerified email at unipd.it
