Cheng-Jun Hu, Associate Professor
Cheng-Jun Hu, Associate Professor
University of Colorado AMC
Verified email at - Homepage
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Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
CJ Hu, LY Wang, LA Chodosh, B Keith, MC Simon
Molecular and cellular biology 23 (24), 9361-9374, 2003
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
KL Covello, J Kehler, H Yu, JD Gordan, AM Arsham, CJ Hu, PA Labosky, ...
Genes & development 20 (5), 557-570, 2006
HIF-2α promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
JD Gordan, JA Bertout, CJ Hu, JA Diehl, MC Simon
Cancer cell 11 (4), 335-347, 2007
Acute postnatal ablation of Hif-2α results in anemia
M Gruber, CJ Hu, RS Johnson, EJ Brown, B Keith, MC Simon
Proceedings of the National Academy of Sciences 104 (7), 2301-2306, 2007
The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1α and HIF-2α
CJ Hu, A Sataur, L Wang, H Chen, MC Simon
Molecular biology of the cell 18 (11), 4528-4542, 2007
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1α) and HIF-2α in stem cells
CJ Hu, S Iyer, A Sataur, KL Covello, LA Chodosh, MC Simon
Molecular and cellular biology 26 (9), 3514-3526, 2006
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate
H Diez, A Fischer, A Winkler, CJ Hu, AK Hatzopoulos, G Breier, M Gessler
Experimental cell research 313 (1), 1-9, 2007
STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells
MR Pawlus, L Wang, CJ Hu
Oncogene 33 (13), 1670-1679, 2014
Role of hepatic resident and infiltrating macrophages in liver repair after acute injury
Q You, M Holt, H Yin, G Li, CJ Hu, C Ju
Biochemical Pharmacology 86 (6), 836-843, 2013
Treatment of a human breast cancer xenograft with an adenovirus vector containing an interferon gene results in rapid regression due to viral oncolysis and gene therapy.
JF Zhang, C Hu, Y Geng, J Selm, SB Klein, A Orazi, MW Taylor
Proceedings of the National Academy of Sciences 93 (9), 4513-4518, 1996
Metabolic and proliferative state of vascular adventitial fibroblasts in pulmonary hypertension is regulated through a microRNA-124/PTBP1 (polypyrimidine tract binding protein …
H Zhang, D Wang, M Li, L Plecitá-Hlavatá, A D’Alessandro, J Tauber, ...
Circulation 136 (25), 2468-2485, 2017
Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer
JC Villa, D Chiu, AH Brandes, FE Escorcia, CH Villa, WF Maguire, CJ Hu, ...
Cell reports 8 (4), 1077-1092, 2014
Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response
MR Pawlus, CJ Hu
Cellular signalling 25 (9), 1895-1903, 2013
Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia
MR Pawlus, L Wang, K Ware, CJ Hu
Molecular and cellular biology 32 (22), 4595-4610, 2012
Hypoxia Regulates Alternative Splicing of HIF and non-HIF Target GenesHypoxia Regulates Alternative Splicing
JA Sena, L Wang, LE Heasley, CJ Hu
Molecular Cancer Research 12 (9), 1233-1243, 2014
Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension
CJ Hu, JM Poth, H Zhang, A Flockton, A Laux, S Kumar, B McKeon, ...
European Respiratory Journal 54 (6), 2019
PU. 1/Spi-B regulation of c-rel is essential for mature B cell survival
CJ Hu, S Rao, DL Ramirez-Bergeron, LA Garrett-Sinha, S Gerondakis, ...
Immunity 15 (4), 545-555, 2001
Gene therapy with an adeno-associated virus carrying an interferon gene results in tumor growth suppression and regression.
JF Zhang, C Hu, Y Geng, LM Blatt, MW Taylor
Cancer Gene Therapy 3 (1), 31-38, 1996
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells
C Befani, I Mylonis, IM Gkotinakou, P Georgoulias, CJ Hu, G Simos, ...
The international journal of biochemistry & cell biology 45 (11), 2359-2368, 2013
BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes
JA Sena, L Wang, CJ Hu
Molecular and cellular biology 33 (19), 3849-3863, 2013
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