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Sietse Braakman
Sietse Braakman
Verified email at ic.ac.uk
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Cited by
Year
Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma
DR Overby, EH Zhou, R Vargas-Pinto, RM Pedrigi, R Fuchshofer, ...
Proceedings of the national Academy of Sciences 111 (38), 13876-13881, 2014
1762014
Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction
WD Stamer, ST Braakman, EH Zhou, CR Ethier, JJ Fredberg, DR Overby, ...
Progress in retinal and eye research 44, 86-98, 2015
1702015
Biomechanics of subcellular structures by non-invasive Brillouin microscopy
G Antonacci, S Braakman
Scientific reports 6, 37217, 2016
1452016
Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal
ST Braakman, AT Read, DWH Chan, CR Ethier, DR Overby
Experimental eye research 130, 87-96, 2015
682015
Visualisation of three pathways for macromolecule transport across cultured endothelium and their modification by flow
M Ghim, P Alpresa, S Yang, ST Braakman, SG Gray, SJ Sherwin, ...
American Journal of Physiology-Heart and Circulatory Physiology, ajpheart …, 2017
552017
Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells
ST Braakman, RM Pedrigi, AT Read, JAE Smith, WD Stamer, CR Ethier, ...
Experimental eye research 127, 224-235, 2014
482014
Transport across Schlemm's canal endothelium and the blood-aqueous barrier
ST Braakman, JE Moore Jr, CR Ethier, DR Overby
Experimental eye research 146, 17-21, 2016
222016
Evaluation Framework for Systems Models
S Braakman, P Pathmanathan, H Moore
CPT: Pharmacometrics & Systems Pharmacology, 2021
202021
A workflow to detect non-identifiability in parameter estimation using SimBiology
F Augustin, S Braakman, R Paxson
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S84-S84, 2018
32018
A fluorescent permeability assay for Schlemm’s canal endothelial cells in response to stretch
ST Braakman, WD Stamer, DR Overby
Investigative Ophthalmology & Visual Science 55 (13), 5983-5983, 2014
22014
Sphingosine-1-Phosphate signaling in cultured human trabecular meshwork cells
S Braakman, K Perkumas, D Overby, D Woodward, WD Stamer
Investigative Ophthalmology & Visual Science 54 (15), 1995-1995, 2013
12013
Pore Formation is Impaired in Glaucomatous SC Cells Perfused In Vitro
RM Pedrigi, R Gupta, ST Braakman, WD Stamer, CR Ethier, DR Overby
Investigative Ophthalmology & Visual Science 53 (14), 3278-3278, 2012
12012
VISUALIZING PARAMETER SOURCE RELIABILITY AND GLOBAL SENSITIVITY FOR QUANTITATIVE SYSTEMS PHARMACOLOGY (QSP) MODELS.
S Braakman, A Gulati, S Tannenbaum, R Paxson
CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S75-S75, 2020
2020
A WORKFLOW TO DETECT ALIASING AND NON-IDENTIFIABILITY IN PARAMETER ESTIMATION USING SIMBIOLOGY.
ST Braakman, F Augustin, R Paxson
CLINICAL PHARMACOLOGY & THERAPEUTICS 105, S53-S53, 2019
2019
Stretch-Dependent Pore Formation in Glaucomatous Schlemm’s Canal Cells
DR Overby, S Braakman, A Spenlehauer, JR Rodrigues, C Teal, AT Read, ...
Investigative Ophthalmology & Visual Science 58 (8), 3773-3773, 2017
2017
Colocalization of segmental outflow and endogenous eNOS activity in the conventional outflow pathway of mice
JYH Chang, ST Braakman, Z Mohri, P Weinberg, CR Ethier, WD Stamer, ...
Investigative Ophthalmology & Visual Science 56 (7), 3276-3276, 2015
2015
The Effect of Cell Stiffness on I-and B-Pore Formation in Schlemm’s Canal Endothelial Cells
DR Overby, A Vahabikashi, R Vargas-Pinto, ST Braakman, R Pedrigi, ...
Investigative Ophthalmology & Visual Science 55 (13), 5982-5982, 2014
2014
Biomechanical regulation of permeability in Schlemm's canal endothelium with respect to glaucoma
S Braakman
Imperial College London, 2014
2014
Elevated stiffness of cultured glaucomatous Schlemm’s canal (SC) cells correlates with impaired pore formation
M Johnson, R Pedrigi, R Vargas-Pinto, R Gupta, S Braakman, C Ethier, ...
Investigative Ophthalmology & Visual Science 54 (15), 379-379, 2013
2013
Schlemm's Canal (SC) Inner Wall Pores Correlate with Segmental Outflow in Human Eyes
C Ethier, S Braakman, A Read, D Chan, D Overby
Investigative Ophthalmology & Visual Science 54 (15), 3538-3538, 2013
2013
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