| Palladium-catalyzed asymmetric allylic alkylation of cyclic dienol carbonates: efficient route to enantioenriched γ-butenolides bearing an all-carbon α-quaternary stereogenic … J Fournier, O Lozano, C Menozzi, S Arseniyadis, J Cossy Angewandte Chemie 125 (4), 2013 | 127 | 2013 |
| A Modular and Scalable One‐Pot Synthesis of Polysubstituted Furans J Fournier, S Arseniyadis, J Cossy Angewandte Chemie 30 (124), 7680-7684, 2012 | 77 | 2012 |
| A palladium-catalyzed asymmetric allylic alkylation approach to α-quaternary γ-butyrolactones M Nascimento de Oliveira, J Fournier, S Arseniyadis, J Cossy Organic letters 19 (1), 14-17, 2017 | 57 | 2017 |
| Discovery of potent and selective non-nucleotide small molecule inhibitors of CD73 JW Beatty, EA Lindsey, R Thomas-Tran, L Debien, D Mandal, JL Jeffrey, ... Journal of medicinal chemistry 63 (8), 3935-3955, 2020 | 40 | 2020 |
| Total synthesis of unsymmetrically oxidized nuphar thioalkaloids via copper-catalyzed thiolane assembly JJ Lacharity, J Fournier, P Lu, AK Mailyan, AT Herrmann, A Zakarian Journal of the American Chemical Society 139 (38), 13272-13275, 2017 | 37 | 2017 |
| Synthesis of functionalized dihydrobenzofurans by direct aryl C− O bond formation under mild conditions J Alvarado, J Fournier, A Zakarian Angewandte Chemie 128 (38), 11797-11800, 2016 | 33 | 2016 |
| Discovery of potent and selective PI3Kγ inhibitors SL Drew, R Thomas-Tran, JW Beatty, J Fournier, KV Lawson, DH Miles, ... Journal of Medicinal Chemistry 63 (19), 11235-11257, 2020 | 32 | 2020 |
| Palladium-catalyzed allylic alkylation of allyl dienol carbonates: reactivity, regioselectivity, enantioselectivity, and synthetic applications S Arseniyadis, J Fournier, S Thangavelu, O Lozano, S Prevost, ... Synlett 24 (18), 2350-2364, 2013 | 32 | 2013 |
| Discovery of potent and selective 7-azaindole isoindolinone-based PI3Kγ inhibitors DH Miles, X Yan, R Thomas-Tran, J Fournier, EU Sharif, SL Drew, G Mata, ... ACS Medicinal Chemistry Letters 11 (11), 2244-2252, 2020 | 15 | 2020 |
| Design, synthesis, and structure–activity relationship optimization of pyrazolopyrimidine amide inhibitors of phosphoinositide 3-kinase γ (PI3Kγ) G Mata, DH Miles, SL Drew, J Fournier, KV Lawson, AK Mailyan, ... Journal of Medicinal Chemistry 65 (2), 1418-1444, 2021 | 9 | 2021 |
| Development of a Scalable Method for Manufacturing the Central Core of CD73 Inhibitor AB680 J Fournier, X Yan, AT Tran, RL Grange, SD Jacob, J Kalisiak, KV Lawson, ... Organic Process Research & Development 25 (1), 157-162, 2020 | 5 | 2020 |
| Total Synthesis of Covalent Cysteine Protease Inhibitor N-Desmethyl Thalassospiramide C and Crystallographic Evidence for Its Mode of Action J Fournier, K Chen, AK Mailyan, JJ Jackson, BO Buckman, K Emayan, ... Organic letters 21 (2), 508-512, 2019 | 4 | 2019 |
| 46P AB521, a clinical-stage, potent, and selective Hypoxia-Inducible Factor (HIF)-2α inhibitor, for the treatment of renal cell carcinoma KV Lawson, KES Gauthier, D Piovesan, A Mailyan, G Mata, JTA Fournier, ... Annals of Oncology 33, S21, 2022 | 2 | 2022 |
| Inhibitors of hif-2alpha JW Beatty, SL Drew, JTA Fournier, T Guney, SD Jacob, KV Lawson, ... US Patent App. 17/777,103, 2023 | 1 | 2023 |
| Tetralin and tetrahydroquinoline compounds as inhibitors of HIF-2α JW Beatty, SL Drew, M Epplin, JTA Fournier, GAL Balint, T Guney, ... US Patent 11,407,712, 2022 | 1 | 2022 |
| Abstract P206: AB521 potently and selectively inhibits pro-tumorigenic gene transcription by Hypoxia-Inducible Factor (HIF)-2α in vitro and in vivo KES Gauthier, D Piovesan, S Cho, KV Lawson, PG Schweickert, A Lopez, ... Molecular Cancer Therapeutics 20 (12_Supplement), P206-P206, 2021 | 1 | 2021 |
| Discovery and characterization of AB521, a novel, potent, and selective hypoxia-inducible factor (HIF)-2α inhibitor KV Lawson, KES Gauthier, AK Mailyan, JT Fournier, JW Beatty, SL Drew, ... Cancer Res. 81, 1206, 2021 | 1 | 2021 |
| 2, 3, 5-trisubstituted pyrazolo [1, 5-a] pyrimidine compounds JW BEATTY, SL DREW, JTA FOURNIER, JL JEFFREY, KV LAWSON, ... | 1 | 2020 |
| Evolution of a Chemical Strategy Toward the Synthesis of Unsymmetrically Oxidized Nuphar Alkaloids JJ Lacharity, A Zakarian Synlett 30 (14), 1632-1642, 2019 | 1 | 2019 |
| Inhibitors of hpk1 and methods of use thereof JR Corbin, S Dhanju, CN Foley, J Fournier, PV Kattamuri, MR Leleti, ... US Patent App. 18/219,046, 2024 | | 2024 |
