srigiridhar kotamraju
srigiridhar kotamraju
Principal scientist
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Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms intermediacy of H2O2-and p53-dependent pathways
S Wang, EA Konorev, S Kotamraju, J Joseph, S Kalivendi, ...
Journal of Biological Chemistry 279 (24), 25535-25543, 2004
Doxorubicin-induced apoptosis: implications in cardiotoxicity
B Kalyanaraman, J Joseph, S Kalivendi, S Wang, E Konorev, S Kotamraju
Molecular and cellular biochemistry 234 (1), 119-124, 2002
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen role of reactive oxygen and nitrogen species
S Kotamraju, EA Konorev, J Joseph, B Kalyanaraman
Journal of biological chemistry 275 (43), 33585-33592, 2000
Activation of nuclear factor-κB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide
S Wang, S Kotamraju, E Konorev, S Kalivendi, J Joseph, B Kalyanaraman
Biochemical Journal 367 (3), 729-740, 2002
Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis
A Dhanasekaran, S Kotamraju, SV Kalivendi, T Matsunaga, T Shang, ...
Journal of Biological Chemistry 279 (36), 37575-37587, 2004
Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase Effect of antiapoptotic antioxidants and calcium
SV Kalivendi, S Kotamraju, H Zhao, J Joseph, B Kalyanaraman
Journal of Biological Chemistry 276 (50), 47266-47276, 2001
Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide
A Dhanasekaran, S Kotamraju, C Karunakaran, SV Kalivendi, S Thomas, ...
Free Radical Biology and Medicine 39 (5), 567-583, 2005
Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis
SB Vasamsetti, S Karnewar, AK Kanugula, AR Thatipalli, JM Kumar, ...
Diabetes 64 (6), 2028-2041, 2015
Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells role of oxidant-induced iron signaling in apoptosis
S Kotamraju, CR Chitambar, SV Kalivendi, J Joseph, B Kalyanaraman
Journal of Biological Chemistry 277 (19), 17179-17187, 2002
Oxidative stress–induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: Role of transferrin receptor …
Y Tampo, S Kotamraju, CR Chitambar, SV Kalivendi, A Keszler, J Joseph, ...
Circulation research 92 (1), 56-63, 2003
Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways
S Kotamraju, CL Willams, B Kalyanaraman
Cancer research 67 (15), 7386-7394, 2007
α-Synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells intermediacy of transferrin receptor iron and hydrogen peroxide
SV Kalivendi, S Cunningham, S Kotamraju, J Joseph, CJ Hillard, ...
Journal of Biological Chemistry 279 (15), 15240-15247, 2004
Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway
S Kotamraju, Y Tampo, A Keszler, CR Chitambar, J Joseph, AL Haas, ...
Proceedings of the National Academy of Sciences 100 (19), 10653-10658, 2003
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide
SV Kalivendi, S Kotamraju, S Cunningham, T Shang, CJ Hillard, ...
Biochemical Journal 371 (1), 151-164, 2003
Iron-deficient intestine is more susceptible to peroxidative damage during iron supplementation in rats.
NKM Srigiridhar K
Free Radic Biol Med. 25 (6), 660-665, 1998
Oral repletion of iron induces free radical mediated alterations in the gastrointestinal tract of rat.
SL Srigiridhar K, Nair KM, Subramanian R
Mol Cell Biochem 219 (1-2), 91-98, 2001
Upregulation of immunoproteasomes by nitric oxide: potential antioxidative mechanism in endothelial cells
S Kotamraju, S Matalon, T Matsunaga, T Shang, JM Hickman-Davis, ...
Free Radical Biology and Medicine 40 (6), 1034-1044, 2006
Ceramide-induced Intracellular Oxidant Formation, Iron Signaling, and Apoptosis in Endothelial Cells PROTECTIVE ROLE OF ENDOGENOUS NITRIC OXIDE
T Matsunaga, S Kotamraju, SV Kalivendi, A Dhanasekaran, J Joseph, ...
Journal of Biological Chemistry 279 (27), 28614-28624, 2004
Synthesis of novel 1, 2, 3-triazole substituted-N-alkyl/aryl nitrone derivatives, their anti-inflammatory and anticancer activity
PS Rao, C Kurumurthy, B Veeraswamy, GS Kumar, Y Poornachandra, ...
European journal of medicinal chemistry 80, 184-191, 2014
Hydrogen peroxide induces nitric oxide and proteosome activity in endothelial cells: a bell-shaped signaling response
S Thomas, S Kotamraju, J Zielonka, DR Harder, B Kalyanaraman
Free Radical Biology and Medicine 42 (7), 1049-1061, 2007
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