Follow
Finny S. Varghese
Finny S. Varghese
Department of Medical Microbiology, Radboud University Medical Center
Verified email at radboudumc.nl
Title
Cited by
Cited by
Year
Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses
FS Varghese, P Kaukinen, S Gläsker, M Bespalov, L Hanski, ...
Antiviral research 126, 117-124, 2016
2222016
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1722022
The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase signaling
FS Varghese, B Thaa, SN Amrun, D Simarmata, K Rausalu, TA Nyman, ...
Journal of virology 90 (21), 9743-9757, 2016
1472016
Differential phosphatidylinositol-3-kinase-Akt-mTOR activation by Semliki Forest and chikungunya viruses is dependent on nsP3 and connected to replication complex internalization
B Thaa, R Biasiotto, K Eng, M Neuvonen, B Götte, L Rheinemann, ...
Journal of virology 89 (22), 11420-11437, 2015
1142015
Obatoclax inhibits alphavirus membrane fusion by neutralizing the acidic environment of endocytic compartments
FS Varghese, K Rausalu, M Hakanen, S Saul, BM Kümmerer, P Susi, ...
Antimicrobial agents and chemotherapy 61 (3), 10.1128/aac. 02227-16, 2017
702017
Design and validation of novel chikungunya virus protease inhibitors
PK Das, L Puusepp, FS Varghese, A Utt, T Ahola, DG Kananovich, ...
Antimicrobial agents and chemotherapy 60 (12), 7382-7395, 2016
672016
Berberine and obatoclax inhibit SARS-Cov-2 replication in primary human nasal epithelial cells in vitro
FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ...
Viruses 13 (2), 282, 2021
632021
Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue
K Rausalu, A Utt, T Quirin, FS Varghese, E Žusinaite, PK Das, T Ahola, ...
Scientific reports 6 (1), 37124, 2016
612016
Natural variation in resistance to virus infection in dipteran insects
WH Palmer, FS Varghese, RP Van Rij
Viruses 10 (3), 118, 2018
602018
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
532020
Population genomics in the arboviral vector Aedes aegypti reveals the genomic architecture and evolution of endogenous viral elements
CM Crava, FS Varghese, E Pischedda, R Halbach, U Palatini, ...
Molecular ecology 30 (7), 1594-1611, 2021
392021
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
362020
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
252023
Natural variation in resistance to virus infection in dipteran insects. Viruses 10: 118
WH Palmer, FS Varghese, RP Van Rij
72018
Insect virus discovery by metagenomic and cell culture-based approaches
FS Varghese, RP van Rij
Viral Metagenomics: Methods and Protocols, 197-213, 2018
72018
Posaconazole inhibits multiple steps of the alphavirus replication cycle
FS Varghese, F Meutiawati, M Teppor, S Jacobs, C de Keyzer, ...
Antiviral research 197, 105223, 2022
52022
Posaconazole is a novel inhibitor for alphavirus viral entry
FS Varghese, F Meutiawati, M Teppor, A Merits, RP Rij
Access Microbiology 1 (10), 41, 2019
42019
Cracking the code of chikungunya virus: inhibitors as tools to explore alphavirus biology
FS Varghese
Helsingin yliopisto, 2016
12016
Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro (preprint)
FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ...
2020
Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses (preprint)
K Kistler, T Bedford, A Undale, K Arora, NM Arora, BPD Purkayastha, ...
2020
The system can't perform the operation now. Try again later.
Articles 1–20