Follow
Alexandr Kornev
Alexandr Kornev
Verified email at ucsd.edu - Homepage
Title
Cited by
Cited by
Year
Protein kinases: evolution of dynamic regulatory proteins
SS Taylor, AP Kornev
Trends in biochemical sciences 36 (2), 65-77, 2011
10012011
Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism
AP Kornev, NM Haste, SS Taylor, LF Ten Eyck
Proceedings of the National Academy of Sciences 103 (47), 17783-17788, 2006
8602006
Assembly of allosteric macromolecular switches: lessons from PKA
SS Taylor, R Ilouz, P Zhang, AP Kornev
Nature reviews Molecular cell biology 13 (10), 646-658, 2012
4892012
A helix scaffold for the assembly of active protein kinases
AP Kornev, SS Taylor, LF Ten Eyck
Proceedings of the National Academy of Sciences 105 (38), 14377-14382, 2008
4852008
PKA: lessons learned after twenty years
SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013
3122013
Defining the conserved internal architecture of a protein kinase
AP Kornev, SS Taylor
Biochimica Et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 440-444, 2010
3062010
Allosteric activation of functionally asymmetric RAF kinase dimers
J Hu, EC Stites, H Yu, EA Germino, HS Meharena, PJS Stork, AP Kornev, ...
Cell 154 (5), 1036-1046, 2013
3032013
Dynamics-driven allostery in protein kinases
AP Kornev, SS Taylor
Trends in biochemical sciences 40 (11), 628-647, 2015
2772015
Dynamic architecture of a protein kinase
CL McClendon, AP Kornev, MK Gilson, SS Taylor
Proceedings of the National Academy of Sciences 111 (43), E4623-E4631, 2014
2702014
The cAMP binding domain: an ancient signaling module
HM Berman, LF Ten Eyck, DS Goodsell, NM Haste, A Kornev, SS Taylor
Proceedings of the National Academy of Sciences 102 (1), 45-50, 2005
2602005
Evolution of the eukaryotic protein kinases as dynamic molecular switches
SS Taylor, MM Keshwani, JM Steichen, AP Kornev
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
2492012
Dynamics connect substrate recognition to catalysis in protein kinase A
LR Masterson, C Cheng, T Yu, M Tonelli, A Kornev, SS Taylor, G Veglia
Nature chemical biology 6 (11), 821-828, 2010
2212010
Deciphering the structural basis of eukaryotic protein kinase regulation
HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ...
PLoS biology 11 (10), e1001680, 2013
2132013
Structure and allostery of the PKA RIIβ tetrameric holoenzyme
P Zhang, EV Smith-Nguyen, MM Keshwani, MS Deal, AP Kornev, ...
Science 335 (6069), 712-716, 2012
1802012
Kinases and pseudokinases: lessons from RAF
AS Shaw, AP Kornev, J Hu, LG Ahuja, SS Taylor
Molecular and cellular biology 34 (9), 1538-1546, 2014
1582014
Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF
J Hu, H Yu, AP Kornev, J Zhao, EL Filbert, SS Taylor, AS Shaw
Proceedings of the National Academy of Sciences 108 (15), 6067-6072, 2011
1482011
Kinase regulation by hydrophobic spine assembly in cancer
J Hu, LG Ahuja, HS Meharena, N Kannan, AP Kornev, SS Taylor, ...
Molecular and cellular biology 35 (1), 264-276, 2015
1062015
A dynamic hydrophobic core orchestrates allostery in protein kinases
J Kim, LG Ahuja, FA Chao, Y Xia, CL McClendon, AP Kornev, SS Taylor, ...
Science advances 3 (4), e1600663, 2017
1032017
Allostery through the computational microscope: cAMP activation of a canonical signalling domain
RD Malmstrom, AP Kornev, SS Taylor, RE Amaro
Nature communications 6 (1), 7588, 2015
952015
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif
TR Baffi, G Lordén, JM Wozniak, A Feichtner, W Yeung, AP Kornev, ...
Science signaling 14 (678), eabe4509, 2021
742021
The system can't perform the operation now. Try again later.
Articles 1–20