Prabakaran Ponraj
Prabakaran Ponraj
Principal Scientist
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ProTherm and ProNIT: thermodynamic databases for proteins and protein–nucleic acid interactions
MDS Kumar, KA Bava, MM Gromiha, P Prabakaran, K Kitajima, H Uedaira, ...
Nucleic acids research 34 (suppl_1), D204-D206, 2006
Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies
Z Zhu, S Chakraborti, Y He, A Roberts, T Sheahan, X Xiao, LE Hensley, ...
Proceedings of the National Academy of Sciences 104 (29), 12123-12128, 2007
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design …
X Xiao, W Chen, Y Feng, Z Zhu, P Prabakaran, Y Wang, MY Zhang, ...
Biochemical and biophysical research communications 390 (3), 404-409, 2009
Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
P Prabakaran, J Gan, Y Feng, Z Zhu, V Choudhry, X Xiao, X Ji, ...
Journal of Biological Chemistry 281 (23), 15829-15836, 2006
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies
T Ying, L Du, TW Ju, P Prabakaran, CCY Lau, L Lu, Q Liu, L Wang, ...
Journal of virology 88 (14), 7796-7805, 2014
A model of the ACE2 structure and function as a SARS-CoV receptor
P Prabakaran, X Xiao, DS Dimitrov
Biochemical and biophysical research communications 314 (1), 235-241, 2004
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
Z Zhu, HR Qin, W Chen, Q Zhao, X Shen, R Schutte, Y Wang, G Ofek, ...
Journal of virology 85 (21), 11401-11408, 2011
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody
T Ying, P Prabakaran, L Du, W Shi, Y Feng, Y Wang, L Wang, W Li, ...
Nature communications 6 (1), 8223, 2015
Antibody aggregation: insights from sequence and structure
W Li, P Prabakaran, W Chen, Z Zhu, Y Feng, DS Dimitrov
Antibodies 5 (3), 19, 2016
Engineered human antibody constant domains with increased stability
R Gong, BK Vu, Y Feng, DRA Prieto, MA Dyba, JD Walsh, P Prabakaran, ...
Journal of biological chemistry 284 (21), 14203-14210, 2009
The SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterization
S Chakraborti, P Prabakaran, X Xiao, DS Dimitrov
Virology journal 2, 1-10, 2005
Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugar
Z Zhu, B Ramakrishnan, J Li, Y Wang, Y Feng, P Prabakaran, ...
MAbs 6 (5), 1190-1200, 2014
Copper (II) complexes with unusual axial phenolate coordination as structural models for the active site in galactose oxidase: X-ray crystal structures and spectral and redox …
M Vaidyanathan, R Viswanathan, M Palaniandavar, T Balasubramanian, ...
Inorganic chemistry 37 (25), 6418-6427, 1998
Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations
P Prabakaran, W Chen, MG Singarayan, CC Stewart, E Streaker, Y Feng, ...
Immunogenetics 64, 337-350, 2012
ProTherm, version 2.0: thermodynamic database for proteins and mutants
MM Gromiha, J An, H Kono, M Oobatake, H Uedaira, P Prabakaran, ...
Nucleic acids research 28 (1), 283-285, 2000
Thermodynamic database for protein–nucleic acid interactions (ProNIT)
P Prabakaran, J An, MM Gromiha, S Selvaraj, H Uedaira, H Kono, A Sarai
Bioinformatics 17 (11), 1027-1034, 2001
Improved breadth and potency of an HIV-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning
MY Zhang, Y Shu, D Rudolph, P Prabakaran, AF Labrijn, MB Zwick, ...
Journal of molecular biology 335 (1), 209-219, 2004
ProTherm, thermodynamic database for proteins and mutants: developments in version 3.0
MM Gromiha, H Uedaira, J An, S Selvaraj, P Prabakaran, A Sarai
Nucleic acids research 30 (1), 301-302, 2002
Potent human monoclonal antibodies against SARS CoV, Nipah and Hendra viruses
P Prabakaran, Z Zhu, X Xiao, A Biragyn, AS Dimitrov, CC Broder, ...
Expert opinion on biological therapy 9 (3), 355-368, 2009
Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains
W Chen, Y Feng, P Prabakaran, T Ying, Y Wang, J Sun, CDS Macedo, ...
Journal of virology 88 (2), 1125-1139, 2014
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