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Gregorio Valdez
Gregorio Valdez
Verified email at brown.edu
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Year
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
AH Williams, G Valdez, V Moresi, X Qi, J McAnally, JL Elliott, ...
Science 326 (5959), 1549-1554, 2009
8432009
Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise
G Valdez, JC Tapia, H Kang, GD Clemenson Jr, FH Gage, JW Lichtman, ...
Proceedings of the National Academy of Sciences 107 (33), 14863-14868, 2010
5212010
A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling
R Kuruvilla, LS Zweifel, NO Glebova, BE Lonze, G Valdez, H Ye, DD Ginty
Cell 118 (2), 243-255, 2004
4212004
Shared resistance to aging and ALS in neuromuscular junctions of specific muscles
G Valdez, JC Tapia, JW Lichtman, MA Fox, JR Sanes
PloS one 7 (4), e34640, 2012
2332012
Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes
Y Shao, W Akmentin, JJ Toledo-Aral, J Rosenbaum, G Valdez, JB Cabot, ...
The Journal of cell biology 157 (4), 679-691, 2002
2312002
Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors
G Valdez, W Akmentin, P Philippidou, R Kuruvilla, DD Ginty, S Halegoua
Journal of Neuroscience 25 (21), 5236-5247, 2005
1812005
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
H Nishimune, G Valdez, G Jarad, CL Moulson, U Müller, JH Miner, ...
The Journal of cell biology 182 (6), 1201-1215, 2008
1422008
Agrin and synaptic laminin are required to maintain adult neuromuscular junctions
MA Samuel, G Valdez, JC Tapia, JW Lichtman, JR Sanes
Public Library of Science 7 (10), e46663, 2012
1262012
Trk-signaling endosomes are generated by Rac-dependent macroendocytosis
G Valdez, P Philippidou, J Rosenbaum, W Akmentin, Y Shao, S Halegoua
Proceedings of the National Academy of Sciences 104 (30), 12270-12275, 2007
1162007
The mammalian exocyst, a complex required for exocytosis, inhibits tubulin polymerization
S Wang, Y Liu, CL Adamson, G Valdez, W Guo, SC Hsu
Journal of Biological Chemistry 279 (34), 35958-35966, 2004
892004
Podosomes are present in a postsynaptic apparatus and participate in its maturation
TJ Proszynski, J Gingras, G Valdez, K Krzewski, JR Sanes
Proceedings of the National Academy of Sciences 106 (43), 18373-18378, 2009
872009
Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis–causing mutations
SK Vaughan, Z Kemp, T Hatzipetros, F Vieira, G Valdez
Journal of Comparative Neurology 523 (17), 2477-2494, 2015
852015
Loss of CLOCK results in dysfunction of brain circuits underlying focal epilepsy
P Li, X Fu, NA Smith, J Ziobro, J Curiel, MJ Tenga, B Martin, S Freedman, ...
Neuron 96 (2), 387-401. e6, 2017
752017
Presynaptic calcium channels and α3‐integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components
SS Carlson, G Valdez, JR Sanes
Journal of neurochemistry 115 (3), 654-666, 2010
722010
The role of muscle microRNAs in repairing the neuromuscular junction
G Valdez, MP Heyer, G Feng, JR Sanes
PloS one 9 (3), e93140, 2014
682014
NMJ maintenance and repair in aging
T Taetzsch, G Valdez
Current opinion in physiology 4, 57-64, 2018
662018
VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions
S Sugita, LL Fleming, C Wood, SK Vaughan, MPSM Gomes, W Camargo, ...
Skeletal muscle 6, 1-17, 2016
662016
Muscle fibers secrete FGFBP1 to slow degeneration of neuromuscular synapses during aging and progression of ALS
T Taetzsch, MJ Tenga, G Valdez
Journal of Neuroscience 37 (1), 70-82, 2017
652017
Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones
D Bonanomi, EF Fornasiero, G Valdez, S Halegoua, F Benfenati, ...
Journal of cell science 121 (22), 3757-3769, 2008
642008
Trk retrograde signaling requires persistent, Pincher-directed endosomes
P Philippidou, G Valdez, W Akmentin, WJ Bowers, HJ Federoff, ...
Proceedings of the National Academy of Sciences 108 (2), 852-857, 2011
632011
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