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Junichi Sugihara
Junichi Sugihara
University Health Network
Verified email at uhnresearch.ca
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Cited by
Year
YidC assists the stepwise and stochastic folding of membrane proteins
T Serdiuk, D Balasubramaniam, J Sugihara, SA Mari, HR Kaback, ...
Nature chemical biology 12 (11), 911-917, 2016
792016
Probing of the rates of alternating access in LacY with Trp fluorescence
I Smirnova, V Kasho, J Sugihara, HR Kaback
Proceedings of the National Academy of Sciences 106 (51), 21561-21566, 2009
622009
Residues in the H+ Translocation Site Define the pKa for Sugar Binding to LacY
I Smirnova, V Kasho, J Sugihara, JY Choe, HR Kaback
Biochemistry 48 (37), 8852-8860, 2009
592009
Substrate-induced changes in the structural properties of LacY
T Serdiuk, MG Madej, J Sugihara, S Kawamura, SA Mari, HR Kaback, ...
Proceedings of the National Academy of Sciences 111 (16), E1571-E1580, 2014
432014
Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding
I Smirnova, V Kasho, J Sugihara, HR Kaback
Proceedings of the National Academy of Sciences 108 (37), 15147-15151, 2011
422011
Trp replacements for tightly interacting Gly–Gly pairs in LacY stabilize an outward-facing conformation
I Smirnova, V Kasho, J Sugihara, HR Kaback
Proceedings of the National Academy of Sciences 110 (22), 8876-8881, 2013
402013
Role of protons in sugar binding to LacY
I Smirnova, V Kasho, J Sugihara, JL Vázquez-Ibar, HR Kaback
Proceedings of the National Academy of Sciences 109 (42), 16835-16840, 2012
362012
Observing a lipid-dependent alteration in single lactose permeases
T Serdiuk, J Sugihara, SA Mari, HR Kaback, DJ Müller
Structure 23 (4), 754-761, 2015
342015
pKa of Glu325 in LacY
N Grytsyk, J Sugihara, HR Kaback, P Hellwig
Proceedings of the National Academy of Sciences 114 (7), 1530-1535, 2017
282017
Sugar recognition by CscB and LacY
J Sugihara, I Smirnova, V Kasho, HR Kaback
Biochemistry 50 (51), 11009-11014, 2011
252011
Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy
J Sugihara, L Sun, N Yan, HR Kaback
Proceedings of the National Academy of Sciences 109 (37), 14847-14851, 2012
202012
Ischemia-reperfusion injury in a simulated lung transplant setting differentially regulates transcriptomic profiles between human lung endothelial and epithelial cells
G Saren, A Wong, YB Lu, C Baciu, W Zhou, R Zamel, S Soltanieh, ...
Cells 10 (10), 2713, 2021
172021
Arg302 governs the pKa of Glu325 in LacY
N Grytsyk, AF Santos Seiça, J Sugihara, HR Kaback, P Hellwig
Proceedings of the National Academy of Sciences 116 (11), 4934-4939, 2019
122019
Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model
M Yoshida, H Oishi, T Martinu, DM Hwang, H Takizawa, J Sugihara, ...
Oncotarget 9 (9), 8489, 2018
102018
XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes
Y Wang, YY Xiang, J Sugihara, WY Lu, XH Liao, P Arvan, S Refetoff, ...
Thyroid 32 (2), 128-137, 2022
62022
XB130 deficiency causes congenital hypothyroidism in mice due to disorganized apical membrane structure and function of thyrocytes
Y Wang, H Shimizu, YY Xiang, J Sugihara, WY Lu, XH Liao, HR Cho, ...
Thyroid 31 (11), 1650-1661, 2021
62021
Pathogenesis of Multinodular Goiter in Elderly XB130-Deficient Mice: Alteration of Thyroperoxidase Affinity with Iodide and Hydrogen Peroxide
HR Cho, J Sugihara, H Shimizu, YY Xiang, X Bai, Y Wang, XH Liao, ...
Thyroid 32 (4), 385-396, 2022
32022
Thyroidal transcriptomic profiles of pathoadaptive responses to congenital hypothyroidism in XB130 knockout mice
J Sugihara, A Wong, H Shimizu, J Zhao, HR Cho, Y Wang, S Refetoff, ...
Cells 11 (6), 975, 2022
22022
L-alanyl-L-glutamine improves lung performance during ex vivo lung perfusion: from cellular mechanism to porcine donor lungs
L Huang, RN Vellanki, J Sugihara, X Gao, L Jing, A Gower, S Soltanieh, ...
The Journal of Heart and Lung Transplantation 39 (4), S197-S198, 2020
12020
Thyroid hormone protects human lung epithelial cells from cold preservation and warm reperfusion-induced injury
D Bojic, T Aujla, J Sugihara, A Wong, S Keshavjee, M Liu
Journal of Translational Medicine 22 (1), 221, 2024
2024
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