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Chetan Rathi
Chetan Rathi
Clinical Pharmacologist, GSK
Verified email at gsk.com
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Cited by
Cited by
Year
Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: in vitro and pharmacokinetics studies
RS Bhatta, H Chandasana, YS Chhonker, C Rathi, D Kumar, K Mitra, ...
International journal of pharmaceutics 432 (1-2), 105-112, 2012
2322012
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux
RE Lee, JG Hurdle, J Liu, DF Bruhn, T Matt, MS Scherman, PK Vaddady, ...
Nature medicine 20 (2), 152-158, 2014
1842014
Clinical pharmacology of bispecific antibody constructs
C Rathi, B Meibohm
The Journal of Clinical Pharmacology 55 (S3), S21-S28, 2015
442015
Translational PK/PD of anti-infective therapeutics
C Rathi, RE Lee, B Meibohm
Drug Discovery Today: Technologies 21, 41-49, 2016
332016
Bioanalytical method development and validation of natamycin in rabbit tears and its application to ocular pharmacokinetic studies
RS Bhatta, H Chandasana, C Rathi, D Kumar, YS Chhonker, GK Jain
Journal of pharmaceutical and biomedical analysis 54 (5), 1096-1100, 2011
322011
Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS …
NM Midde, MA Rahman, C Rathi, J Li, B Meibohm, W Li, S Kumar
PloS one 11 (2), e0149225, 2016
272016
Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections
DF Bruhn, SL Waidyarachchi, DB Madhura, D Shcherbakov, Z Zheng, ...
Science translational medicine 7 (288), 288ra75-288ra75, 2015
222015
Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors
AB El-Khoueiry, J Clarke, T Neff, T Crossman, N Ratia, C Rathi, P Noto, ...
British journal of cancer 129 (2), 309-317, 2023
162023
LC–MS method for determination of amphotericin B in rabbit tears and its application to ocular pharmacokinetic study
RS Bhatta, C Rathi, H Chandasana, D Kumar, YS Chhonker, GK Jain
Chromatographia 73 (5), 487-493, 2011
132011
Population Pharmacokinetics of Belantamab Mafodotin, a BCMA‐targeting Agent in Patients with Relapsed/Refractory Multiple Myeloma
C Rathi, J Collins, H Struemper, J Opalinska, RC Jewell, G Ferron‐Brady
CPT: Pharmacometrics & Systems Pharmacology, 2021
112021
Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis
PK Vaddady, A Trivedi, C Rathi, DB Madhura, J Liu, RE Lee, B Meibohm
European Journal of Pharmaceutical Sciences 127, 233-239, 2019
112019
Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice
C Rathi, PB Lukka, S Wagh, RE Lee, AJ Lenaerts, M Braunstein, A Hickey, ...
Tuberculosis 114, 119-122, 2019
102019
Model-based exposure-response assessment for spectinamide 1810 in a mouse model of tuberculosis
S Wagh, C Rathi, PB Lukka, K Parmar, Z Temrikar, J Liu, MS Scherman, ...
Antimicrobial Agents and Chemotherapy, AAC. 01744-20, 2021
92021
Exposure–Response Analyses for Therapeutic Dose Selection of Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma
G Ferron‐Brady, C Rathi, J Collins, H Struemper, J Opalinska, S Visser, ...
Clinical Pharmacology & Therapeutics, 2021
82021
Exposure-response (ER) for ocular safety endpoints for belantamab mafodotin (belamaf), a B-Cell Maturation Antigen (BCMA)-targeting agent, in patients with relapsed/refractory …
G Ferron-Brady, C Rathi, J Collins, H Struemper, J Opalinska, RC Jewell
Blood 136, 20-21, 2020
42020
Pharmacokinetics of Peptides and Proteins
C Rathi, B Meibohm
Reviews in Cell Biology and Molecular Medicine 1 (2), 300-326, 2006
42006
Abstract CT196: Therapeutic dose selection for belantamab mafodotin, a BCMA-targeting agent, in patients with relapsed/refractory multiple myeloma (RRMM): Application of …
G Ferron-Brady, C Rathi, J Collins, H Struemper, J Opalinska, RC Jewell
Cancer Research 80 (16 Supplement), CT196-CT196, 2020
32020
A phase I/II study of GSK3145095 alone and in combination with anticancer agents including pembrolizumab in adults with selected solid tumors.
DJ Cohen, S Pant, B O'Neil, J Marinis, J Winnberg, CM Ahlers, J Callaway, ...
Journal of Clinical Oncology 37 (15_suppl), TPS4165-TPS4165, 2019
32019
Should Race‐Genotype Interactions Be Considered in the Global Development of CYP2C19 Substrates? A Proposed Framework Using Physiologically Based Pharmacokinetic Modeling
C Patel, C Rathi, K Venkatakrishnan
The Journal of Clinical Pharmacology 57 (4), 417-421, 2017
32017
Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation in the Development of Spectinamides, a Novel Class of Anti-Tuberculosis Agents
C Rathi
The University of Tennessee Health Science Center, 2017
22017
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