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Lei Miao
Lei Miao
Postdoctoral Research Associate
Verified email at mit.edu
Title
Cited by
Cited by
Year
Delivering the messenger: advances in technologies for therapeutic mRNA delivery
PS Kowalski, A Rudra, L Miao, DG Anderson
Molecular Therapy 27 (4), 710-728, 2019
9312019
mRNA vaccine for cancer immunotherapy
L Miao, Y Zhang, L Huang
Molecular cancer 20 (1), 41, 2021
6452021
Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
L Miao, L Li, Y Huang, D Delcassian, J Chahal, J Han, Y Shi, K Sadtler, ...
Nature biotechnology 37 (10), 1174-1185, 2019
5222019
Self-assembled redox dual-responsive prodrug-nanosystem formed by single thioether-bridged paclitaxel-fatty acid conjugate for cancer chemotherapy
C Luo, J Sun, D Liu, B Sun, L Miao, S Musetti, J Li, X Han, Y Du, L Li, ...
Nano letters 16 (9), 5401-5408, 2016
3872016
Combination immunotherapy of MUC1 mRNA nano-vaccine and CTLA-4 blockade effectively inhibits growth of triple negative breast cancer
L Liu, Y Wang, L Miao, Q Liu, S Musetti, J Li, L Huang
Molecular Therapy 26 (1), 45-55, 2018
3202018
Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles
K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang
ACS nano 11 (5), 4916-4925, 2017
2452017
Stromal barriers and strategies for the delivery of nanomedicine to desmoplastic tumors
L Miao, CM Lin, L Huang
Journal of Controlled Release 219, 192-204, 2015
2372015
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer
N Cheng, R Watkins-Schulz, RD Junkins, CN David, BM Johnson, ...
JCI insight 3 (22), 2018
2332018
Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
L Miao, J Lin, Y Huang, L Li, D Delcassian, Y Ge, Y Shi, DG Anderson
Nature communications 11 (1), 2424, 2020
2322020
Targeting tumor-associated fibroblasts for therapeutic delivery in desmoplastic tumors
L Miao, Q Liu, CM Lin, C Luo, Y Wang, L Liu, W Yin, S Hu, WY Kim, ...
Cancer research 77 (3), 719-731, 2017
2132017
Delivery of oligonucleotides with lipid nanoparticles
Y Wang, L Miao, A Satterlee, L Huang
Advanced drug delivery reviews 87, 68-80, 2015
2042015
Esterase‐activated charge‐reversal polymer for fibroblast‐exempt cancer gene therapy
N Qiu, X Liu, Y Zhong, Z Zhou, Y Piao, L Miao, Q Zhang, J Tang, L Huang, ...
Advanced Materials 28 (48), 10613-10622, 2016
2022016
Nanoparticles with precise ratiometric co‐loading and co‐delivery of gemcitabine monophosphate and cisplatin for treatment of bladder cancer
L Miao, S Guo, J Zhang, WY Kim, L Huang
Advanced functional materials 24 (42), 6601-6611, 2014
1892014
The binding site barrier elicited by tumor-associated fibroblasts interferes disposition of nanoparticles in stroma-vessel type tumors
L Miao, JM Newby, CM Lin, L Zhang, F Xu, WY Kim, MG Forest, SK Lai, ...
ACS nano 10 (10), 9243-9258, 2016
1852016
Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation
S Guo, CM Lin, Z Xu, L Miao, Y Wang, L Huang
ACS nano 8 (5), 4996-5009, 2014
1792014
mRNA vaccine with antigen-specific checkpoint blockade induces an enhanced immune response against established melanoma
Y Wang, L Zhang, Z Xu, L Miao, L Huang
Molecular Therapy 26 (2), 420-434, 2018
1722018
Nanoformulations for combination or cascade anticancer therapy
L Miao, S Guo, CM Lin, Q Liu, L Huang
Advanced drug delivery reviews 115, 3-22, 2017
1652017
PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery
Y Zhao, W Wang, S Guo, Y Wang, L Miao, Y Xiong, L Huang
Nature communications 7 (1), 11822, 2016
1622016
Facile fabrication of tumor redox‐sensitive nanoassemblies of small‐molecule oleate prodrug as potent chemotherapeutic nanomedicine
C Luo, J Sun, B Sun, D Liu, L Miao, TJ Goodwin, L Huang, Z He
Small 12 (46), 6353-6362, 2016
1552016
Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy
X Lu, L Miao, W Gao, Z Chen, KJ McHugh, Y Sun, Z Tochka, S Tomasic, ...
Science translational medicine 12 (556), eaaz6606, 2020
1482020
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