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Sylvie Bertholet
Sylvie Bertholet
Director Preclinical Evidence Generation, Preclinical R&D, GSK Vaccines, Rockville MD
Verified email at gsk.com
Title
Cited by
Cited by
Year
Phagosomes are competent organelles for antigen cross-presentation
M Houde, S Bertholet, E Gagnon, S Brunet, G Goyette, A Laplante, ...
Nature 425 (6956), 402-406, 2003
9532003
New horizons in adjuvants for vaccine development
SG Reed, S Bertholet, RN Coler, M Friede
Trends in immunology 30 (1), 23-32, 2009
8982009
CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
Y Belkaid, E Von Stebut, S Mendez, R Lira, E Caler, S Bertholet, MC Udey, ...
The Journal of Immunology 168 (8), 3992-4000, 2002
4052002
Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant
RN Coler, S Bertholet, M Moutaftsi, JA Guderian, HP Windish, SL Baldwin, ...
PloS one 6 (1), e16333, 2011
3982011
A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis
S Bertholet, GC Ireton, DJ Ordway, HP Windish, SO Pine, M Kahn, T Phan, ...
Science translational medicine 2 (53), 53ra74-53ra74, 2010
3482010
Programmed cell death in the unicellular protozoan parasite Leishmania
N Lee, S Bertholet, A Debrabant, J Muller, R Duncan, HL Nakhasi
Cell Death & Differentiation 9 (1), 53-64, 2002
3472002
Unleashing the potential of NOD-and Toll-like agonists as vaccine adjuvants
C Maisonneuve, S Bertholet, DJ Philpott, E De Gregorio
Proceedings of the National Academy of Sciences 111 (34), 12294-12299, 2014
3192014
Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice
A Hekele, S Bertholet, J Archer, DG Gibson, G Palladino, LA Brito, ...
Emerging microbes & infections 2 (1), 1-7, 2013
2482013
The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect
S Calabro, E Tritto, A Pezzotti, M Taccone, A Muzzi, S Bertholet, ...
Vaccine 31 (33), 3363-3369, 2013
2132013
Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosis
S Bertholet, GC Ireton, M Kahn, J Guderian, R Mohamath, N Stride, ...
The Journal of Immunology 181 (11), 7948-7957, 2008
2062008
Programmed cell death in trypanosomatids and other unicellular organisms
A Debrabant, N Lee, S Bertholet, R Duncan, HL Nakhasi
International journal for parasitology 33 (3), 257-267, 2003
2032003
Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus
F Bagnoli, MR Fontana, E Soldaini, RPN Mishra, L Fiaschi, E Cartocci, ...
Proceedings of the National Academy of Sciences 112 (12), 3680-3685, 2015
1972015
Inferring Reasons for the Failure of Staphylococcus aureus Vaccines in Clinical Trials
F Bagnoli, S Bertholet, G Grandi
Frontiers in cellular and infection microbiology 2, 16, 2012
1942012
A synthetic adjuvant to enhance and expand immune responses to influenza vaccines
RN Coler, SL Baldwin, N Shaverdian, S Bertholet, SJ Reed, VS Raman, ...
PloS one 5 (10), e13677, 2010
1712010
Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo
S Bertholet, R Goldszmid, A Morrot, A Debrabant, F Afrin, ...
The Journal of Immunology 177 (6), 3525-3533, 2006
1652006
Induction of broad-based immunity and protective efficacy by self-amplifying mRNA vaccines encoding influenza virus hemagglutinin
M Brazzoli, D Magini, A Bonci, S Buccato, C Giovani, R Kratzer, V Zurli, ...
Journal of virology 90 (1), 332-344, 2016
1512016
The importance of adjuvant formulation in the development of a tuberculosis vaccine
SL Baldwin, S Bertholet, VA Reese, LK Ching, SG Reed, RN Coler
The Journal of Immunology 188 (5), 2189-2197, 2012
1432012
Novel platforms for the development of a universal influenza vaccine
A Kumar, TS Meldgaard, S Bertholet
Frontiers in immunology 9, 333832, 2018
1292018
Self-amplifying mRNA vaccines expressing multiple conserved influenza antigens confer protection against homologous and heterosubtypic viral challenge
D Magini, C Giovani, S Mangiavacchi, S Maccari, R Cecchi, JB Ulmer, ...
PloS one 11 (8), e0161193, 2016
1292016
Enhanced humoral and Type 1 cellular immune responses with Fluzone® adjuvanted with a synthetic TLR4 agonist formulated in an emulsion
SL Baldwin, N Shaverdian, Y Goto, MS Duthie, VS Raman, T Evers, ...
Vaccine 27 (43), 5956-5963, 2009
1192009
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