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Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7 R Bremner, A Balmain Cell 61 (3), 407-417, 1990 | 345 | 1990 |
Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma D Chen, I Livne-bar, JL Vanderluit, RS Slack, M Agochiya, R Bremner Cancer cell 5 (6), 539-551, 2004 | 326 | 2004 |
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells JL Chong, PL Wenzel, MT Sáenz-Robles, V Nair, A Ferrey, JP Hagan, ... Nature 462 (7275), 930-934, 2009 | 282 | 2009 |
Direct transcriptional repression by pRB and its reversal by specific cyclins R Bremner, BL Cohen, M Sopta, PA Hamel, CJ Ingles, BL Gallie, ... Molecular and Cellular Biology 15 (6), 3256-3265, 1995 | 249 | 1995 |
Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography MD Fischer, G Huber, SC Beck, N Tanimoto, R Muehlfriedel, E Fahl, ... PloS one 4 (10), e7507, 2009 | 237 | 2009 |
Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice. PA Burns, CJ Kemp, JV Gannon, DP Lane, R Bremner, A Balmain Oncogene 6 (12), 2363-2369, 1991 | 202 | 1991 |
The search for the retinoblastoma cell of origin MA Dyer, R Bremner Nature Reviews Cancer 5 (2), 91-101, 2005 | 201 | 2005 |
Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson, A Kallman, S Zhong, ... Developmental cell 53 (4), 473-491. e9, 2020 | 190 | 2020 |
Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer D DiCiommo, BL Gallie, R Bremner Seminars in cancer biology 10 (4), 255-269, 2000 | 185 | 2000 |
Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage DS Park, EJ Morris, R Bremner, E Keramaris, J Padmanabhan, ... Journal of Neuroscience 20 (9), 3104-3114, 2000 | 181 | 2000 |
Division and apoptosis of E2f-deficient retinal progenitors D Chen, M Pacal, P Wenzel, PS Knoepfler, G Leone, R Bremner Nature 462 (7275), 925-929, 2009 | 173 | 2009 |
Rapid, high level protein production using DNA-based Semliki Forest virus vectors DP DiCiommo, R Bremner Journal of Biological Chemistry 273 (29), 18060-18066, 1998 | 163 | 1998 |
Interferon-γ-induced chromatin remodeling at the CIITA locus is BRG1 dependent SG Pattenden, R Klose, E Karaskov, R Bremner The EMBO journal 21 (8), 1978-1986, 2002 | 137 | 2002 |
A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity E Zacksenhaus, R Bremner, RA Phillips, BL Gallie Molecular and cellular biology 13 (8), 4588-4599, 1993 | 132 | 1993 |
The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers Z Ni, MAE Hassan, Z Xu, T Yu, R Bremner Nature immunology 9 (7), 785-793, 2008 | 126 | 2008 |
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome LE Heisler, D Torti, PC Boutros, J Watson, C Chan, N Winegarden, ... Nucleic acids research 33 (9), 2952-2961, 2005 | 121 | 2005 |
Deletion of RBExons 24 and 25 Causes Low-Penetrance Retinoblastoma R Bremner, DC Du, MJ Connolly-Wilson, P Bridge, KF Ahmad, ... The American Journal of Human Genetics 61 (3), 556-570, 1997 | 119 | 1997 |
Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina I Livne-Bar, M Pacal, MC Cheung, M Hankin, J Trogadis, D Chen, ... Proceedings of the National Academy of Sciences 103 (13), 4988-4993, 2006 | 116 | 2006 |
Apical role for BRG1 in cytokine-induced promoter assembly Z Ni, E Karaskov, T Yu, SM Callaghan, S Der, DS Park, Z Xu, ... Proceedings of the National Academy of Sciences 102 (41), 14611-14616, 2005 | 106 | 2005 |