Stevan R. Hubbard
Stevan R. Hubbard
NYU School of Medicine
Verified email at - Homepage
Cited by
Cited by
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
M Calfon, H Zeng, F Urano, JH Till, SR Hubbard, HP Harding, SG Clark, ...
Nature 415 (6867), 92-96, 2002
Protein tyrosine kinase structure and function
SR Hubbard, JH Till
Annual review of biochemistry 69 (1), 373-398, 2000
Crystal structure of the tyrosine kinase domain of the human insulin receptor
SR Hubbard, L Wei, L Ellis, WA Hendrickson
Nature 372, 22, 1994
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
M Mohammadi, G McMahon, L Sun, C Tang, P Hirth, BK Yeh, ...
Science 276 (5314), 955-960, 1997
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog
SR Hubbard
The EMBO journal 16 (18), 5572-5581, 1997
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
Z Songyang, KL Carraway, MJ Eck, SC Harrison, RA Feldman, ...
Nature 373 (6514), 536-539, 1995
Structural basis for FGF receptor dimerization and activation
AN Plotnikov, J Schlessinger, SR Hubbard, M Mohammadi
Cell 98 (5), 641-650, 1999
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
AD Laird, P Vajkoczy, LK Shawver, A Thurnher, C Liang, M Mohammadi, ...
Cancer Research 60 (15), 4152-4160, 2000
Lrp4 is a receptor for Agrin and forms a complex with MuSK
N Kim, AL Stiegler, TO Cameron, PT Hallock, AM Gomez, JH Huang, ...
Cell 135 (2), 334-342, 2008
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain
M Mohammadi, S Froum, JM Hamby, MC Schroeder, RL Panek, GH Lu, ...
The EMBO journal 17 (20), 5896-5904, 1998
Receptor tyrosine kinases: mechanisms of activation and signaling
SR Hubbard, WT Miller
Current opinion in cell biology 19 (2), 117-123, 2007
Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
M Mohammadi, J Schlessinger, SR Hubbard
Cell 86 (4), 577-587, 1996
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
AN Plotnikov, SR Hubbard, J Schlessinger, M Mohammadi
Cell 101 (4), 413-424, 2000
Autoregulatory mechanisms in protein-tyrosine kinases
SR Hubbard, M Mohammadi, J Schlessinger
Journal of Biological Chemistry 273 (20), 11987-11990, 1998
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase
S Favelyukis, JH Till, SR Hubbard, WT Miller
Nature structural biology 8 (12), 1058-1063, 2001
Juxtamembrane autoinhibition in receptor tyrosine kinases
SR Hubbard
Nature Reviews Molecular Cell Biology 5 (6), 464-471, 2004
Mechanism-based design of a protein kinase inhibitor
K Parang, JH Till, AJ Ablooglu, RA Kohanski, SR Hubbard, PA Cole
Nature structural biology 8 (1), 37-41, 2001
Structural analysis of receptor tyrosine kinases
SR Hubbard
Progress in biophysics and molecular biology 71 (3-4), 343-358, 1999
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling
D Ungureanu, J Wu, T Pekkala, Y Niranjan, C Young, ON Jensen, CF Xu, ...
Nature structural & molecular biology 18 (9), 971-976, 2011
Identification and characterization of zinc binding sites in protein kinase C
WR Bishop, P Kirschmeier, SJ George, SP Cramer, WA Hendrickson
Science 254 (5039), 1776-1779, 1991
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