Alexios N. Matralis
Alexios N. Matralis
Biomedical Sciences Research Center "Alexander Fleming"
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Cited by
Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents
AN Matralis, MG Katselou, A Nikitakis, AP Kourounakis
Journal of medicinal chemistry 54 (15), 5583-5591, 2011
Human isoprenoid synthase enzymes as therapeutic targets
J Park, AN Matralis, AM Berghuis, YS Tsantrizos
Frontiers in chemistry 2, 50, 2014
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: Exploiting phenothiazine’s strong antioxidant activity
AN Matralis, AP Kourounakis
Journal of medicinal chemistry 57 (6), 2568-2581, 2014
Design of more potent squalene synthase inhibitors with multiple activities
AP Kourounakis, AN Matralis, A Nikitakis
Bioorganic & medicinal chemistry 18 (21), 7402-7412, 2010
Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents
A P Kourounakis, M G Katselou, A N Matralis, E M Ladopoulou, ...
Current medicinal chemistry 18 (29), 4418-4439, 2011
Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials
AN Matralis, A Afantitis, V Aidinis
Medicinal research reviews 39 (3), 976-1013, 2019
Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution
EM Ladopoulou, AN Matralis, A Nikitakis, AP Kourounakis
Bioorganic & medicinal chemistry 23 (21), 7015-7023, 2015
Water-Soluble Stoichiometric Polyelectrolyte Complexes Based on Cationic Comb-Type Copolymers
A Matralis, M Sotiropoulou, G Bokias, G Staikos
Macromolecular Chemistry and Physics 207 (12), 1018-1025, 2005
Multi-target drug design approaches for multifactorial diseases: From neurodegenerative to cardiovascular applications
MG Katselou, AN Matralis, AP Kourounakis
Current medicinal chemistry 21 (24), 2743-2787, 2014
Antioxidant Activity of Newly Synthesized 2, 7‐Diazaphenothiazines
B Morak‐Młodawska, K Pluta, AN Matralis, AP Kourounakis
Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2010
Pharmacophore mapping of thienopyrimidine-based monophosphonate (ThP-MP) inhibitors of the human farnesyl pyrophosphate synthase
J Park, CY Leung, AN Matralis, CM Lacbay, M Tsakos, ...
Journal of Medicinal Chemistry 60 (5), 2119-2134, 2017
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites
AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ...
Journal of medicinal chemistry 62 (20), 9217-9235, 2019
New Multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine Derivatives with Antioxidant, Antihyperlipidemic, and Antidiabetic Action
E Ladopoulou, AN Matralis, AP Kourounakis
Journal of Medicinal Chemistry 56 (8), 3330-3338, 2013
Evaluation of two novel antioxidants with differential effects on curcumin-induced apoptosis in C2 skeletal myoblasts; involvement of JNKs
M Peleli, IK Aggeli, AN Matralis, AP Kourounakis, I Beis, C Gaitanaki
Bioorganic & Medicinal Chemistry 23 (3), 390-400, 2015
Developing potential agents against atherosclerosis: design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity
MG Katselou, AN Matralis, AP Kourounakis
European Journal of Medicinal Chemistry 138, 748-760, 2017
Molecular tools that block maturation of the nuclear lamin A and decelerate cancer cell migration
AN Matralis, D Xanthopoulos, G Huot, S Lopes-Paciencia, C Cole, ...
Bioorganic & Medicinal Chemistry 26 (20), 5547-5554, 2018
Targeting the malaria parasite cGMP-dependent protein kinase to develop new drugs
DA Baker, AN Matralis, SA Osborne, JM Large, M Penzo
Frontiers in Microbiology 11, 602803, 2020
Optimizing the pharmacological profile of new bifunctional antihyperlipidemic/antioxidant morpholine derivatives
AN Matralis, AP Kourounakis
ACS medicinal chemistry letters 10 (1), 98-104, 2018
Commonalities between ARDS, pulmonary fibrosis and COVID-19: the potential of autotaxin as a therapeutic target
K Ntatsoulis, T Karampitsakos, E Tsitoura, EA Stylianaki, AN Matralis, ...
Frontiers in Immunology 12, 2021
Balancing antioxidant, hypolipidemic and anti-inflammatory activity in a single agent: The example of 2-hydroxy-2-substituted morpholine, 1, 4-benzoxazine and 1, 4 …
A N Matralis, EI Bavavea, S Incerpi, J Z Pedersen, A P Kourounakis
Current medicinal chemistry 24 (12), 1214-1227, 2017
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