Therapeutic targeting of RNA splicing catalysis through inhibition of protein arginine methylation JY Fong, L Pignata, PA Goy, KC Kawabata, SCW Lee, CM Koh, D Musiani, ... Cancer cell 36 (2), 194-209. e9, 2019 | 212 | 2019 |
p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6 S Phalke, S Mzoughi, M Bezzi, N Jennifer, WC Mok, DHP Low, AA Thike, ... Nucleic acids research 40 (19), 9534-9542, 2012 | 105 | 2012 |
The role of PRDMs in cancer: one family, two sides S Mzoughi, YX Tan, D Low, E Guccione Current opinion in genetics & development 36, 83-91, 2016 | 89 | 2016 |
PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK–ERK signaling S Mzoughi, J Zhang, D Hequet, SX Teo, H Fang, QR Xing, M Bezzi, ... Nature genetics 49 (9), 1354-1363, 2017 | 45 | 2017 |
The duality of PRDM proteins: epigenetic and structural perspectives F Di Tullio, M Schwarz, H Zorgati, S Mzoughi, E Guccione The FEBS journal 289 (5), 1256-1275, 2022 | 33 | 2022 |
Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR M Schwarz, D Torre, D Lozano-Ojalvo, AT Tan, T Tabaglio, S Mzoughi, ... Nature biotechnology 40 (11), 1680-1689, 2022 | 29 | 2022 |
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis S Mzoughi, JY Fong, D Papadopoli, CM Koh, L Hulea, P Pigini, F Di Tullio, ... Nature communications 11 (1), 3520, 2020 | 25 | 2020 |
The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons MKY Seah, Y Wang, PA Goy, HM Loh, WJ Peh, DHP Low, BY Han, ... Development 146 (19), dev170266, 2019 | 23 | 2019 |
Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6 J Trott, Y Alpagu, EK Tan, M Shboul, Y Dawood, M Elsy, H Wollmann, ... Development 147 (21), dev194878, 2020 | 18 | 2020 |
Mutations in PRDM15 are a novel cause of Galloway-Mowat syndrome N Mann, S Mzoughi, R Schneider, SJ Kühl, D Schanze, V Klämbt, S Lovric, ... Journal of the American Society of Nephrology 32 (3), 580-596, 2021 | 17 | 2021 |
T cell immunity is key to the pandemic endgame: How to measure and monitor it M Schwarz, S Mzoughi, D Lozano-Ojalvo, AT Tan, A Bertoletti, ... Current Research in Immunology 3, 215-221, 2022 | 16 | 2022 |
cell immunity is key to the pandemic endgame: How to measure and monitor it. Curr M Schwarz, S Mzoughi, D Lozano-Ojalvo, AT Tan, A Bertoletti, ... Res. Immunol 3, 215-221, 2022 | 15 | 2022 |
PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly S Mzoughi, F Di Tullio, DHP Low, CM Motofeanu, SLM Ong, H Wollmann, ... Science advances 6 (2), eaax9852, 2020 | 14 | 2020 |
Gender differences in the association of ELMO1 genetic variants with type 2 diabetes in Tunisian Arabs A Turki, S Mzoughi, N Mtitaoui, M Khairallah, H Marmouch, S Hammami, ... Journal of endocrinological investigation 41, 285-291, 2018 | 12 | 2018 |
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors E Guccione, M Schwarz, F Di Tullio, S Mzoughi Current opinion in pharmacology 59, 33-42, 2021 | 10 | 2021 |
Androgen receptors in breast cancer: Expression, value and therapeutic prospects D Héquet, S Mzoughi, R Rouzier, E Guccione Bulletin du Cancer 104 (4), 363-369, 2017 | 7 | 2017 |
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation D Torre, YS Fstkchyan, JSY Ho, Y Cheon, RS Patel, EJ Degrace, ... Molecular cell 83 (23), 4255-4271. e9, 2023 | 2 | 2023 |
WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma A Rialdi, M Duffy, AP Scopton, F Fonseca, JN Zhao, M Schwarz, ... Nature Cancer 4 (8), 1157-1175, 2023 | 2 | 2023 |
Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis E Saumweber, S Mzoughi, A Khadra, A Werberger, S Schumann, ... Frontiers in Cell and Developmental Biology 12, 1316048, 2024 | 1 | 2024 |
Methods of treating tumors and cancers having dysregulated wnt signaling pathways E Guccione, A Lujambio, A Dar, A Rialdi, ME Duffy, AP Scopton, ... US Patent App. 18/034,965, 2023 | | 2023 |