Harinath Chakrapani
Harinath Chakrapani
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Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO2) as Antimycobacterial Agents
SR Malwal, D Sriram, P Yogeeswari, VB Konkimalla, H Chakrapani
Journal of medicinal chemistry 55 (1), 553-557, 2012
Esterase Activated Carbonyl Sulfide/Hydrogen Sulfide (H2S) Donors
P Chauhan, P Bora, G Ravikumar, S Jos, H Chakrapani
Organic letters 19 (1), 62-65, 2017
“On demand” redox buffering by H 2 S contributes to antibiotic resistance revealed by a bacteria-specific H 2 S donor
P Shukla, VS Khodade, M SharathChandra, P Chauhan, S Mishra, ...
Chemical science 8 (7), 4967-4972, 2017
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis
G Rai, AA Sayed, WA Lea, HF Luecke, H Chakrapani, S Prast-Nielsen, ...
Journal of medicinal chemistry 52 (20), 6474-6483, 2009
Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and double JS-K, through incorporation into PEG-protected nanoparticles
V Kumar, SY Hong, AE Maciag, JE Saavedra, DH Adamson, ...
Molecular pharmaceutics 7 (1), 291-298, 2010
Enantioselective cyclization/hydrosilylation of 1, 6-enynes catalyzed by a cationic rhodium bis (phosphine) complex
H Chakrapani, C Liu, RA Widenhoefer
Organic Letters 5 (2), 157-159, 2003
Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release
AK Sharma, M Nair, P Chauhan, K Gupta, DK Saini, H Chakrapani
Organic Letters 19 (18), 4822-4825, 2017
The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen Species
AE Maciag, H Chakrapani, JE Saavedra, NL Morris, RJ Holland, ...
Journal of Pharmacology and Experimental Therapeutics 336 (2), 313-320, 2011
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide
P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh
Free Radical Biology and Medicine 84, 344-354, 2015
A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives
VK Pamula, V Srinivasan, H Chakrapani, RB Fair, EJ Toone
18th IEEE International Conference on Micro Electro Mechanical Systems, 2005 …, 2005
Cyclization/hydrosilylation of functionalized 1, 6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands
X Wang, H Chakrapani, JW Madine, MA Keyerleber, RA Widenhoefer
The Journal of organic chemistry 67 (9), 2778-2788, 2002
INDQ/NO, a Bioreductively Activated Nitric Oxide Prodrug
K Sharma, A Iyer, K Sengupta, H Chakrapani
Organic letters 15 (11), 2636-2639, 2013
Nitroreductase-activated nitric oxide (NO) prodrugs
K Sharma, K Sengupta, H Chakrapani
Bioorganic & medicinal chemistry letters 23 (21), 5964-5967, 2013
Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs
H Chakrapani, RC Kalathur, AE Maciag, ML Citro, X Ji, LK Keefer, ...
Bioorganic & medicinal chemistry 16 (22), 9764-9771, 2008
A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
DS Kelkar, G Ravikumar, N Mehendale, S Singh, A Joshi, AK Sharma, ...
Nature chemical biology 15 (2), 169-178, 2019
Reactive Oxygen Species-Triggered Tunable Hydrogen Sulfide Release
P Chauhan, S Jos, H Chakrapani
Organic letters 20 (13), 3766-3770, 2018
The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents
AE Maciag, JE Saavedra, H Chakrapani
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009
Small molecule generators of biologically reactive sulfur species
P Bora, P Chauhan, KA Pardeshi, H Chakrapani
RSC Advances 8 (48), 27359-27374, 2018
Site-directed delivery of nitric oxide to cancers
K Sharma, H Chakrapani
Nitric Oxide 43, 8-16, 2014
Bioreductively Activated Reactive Oxygen Species (ROS) Generators as MRSA Inhibitors
V Khodade, M Sharath Chandra, A Banerjee, S Lahiri, M Pulipeta, ...
ACS Medicinal Chemistry Letters, 2014
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