Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO2) as Antimycobacterial Agents SR Malwal, D Sriram, P Yogeeswari, VB Konkimalla, H Chakrapani Journal of medicinal chemistry 55 (1), 553-557, 2012 | 168 | 2012 |
Esterase Activated Carbonyl Sulfide/Hydrogen Sulfide (H2S) Donors P Chauhan, P Bora, G Ravikumar, S Jos, H Chakrapani Organic letters 19 (1), 62-65, 2017 | 120 | 2017 |
“On demand” redox buffering by H 2 S contributes to antibiotic resistance revealed by a bacteria-specific H 2 S donor P Shukla, VS Khodade, M SharathChandra, P Chauhan, S Mishra, ... Chemical science 8 (7), 4967-4972, 2017 | 112 | 2017 |
Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release AK Sharma, M Nair, P Chauhan, K Gupta, DK Saini, H Chakrapani Organic Letters 19 (18), 4822-4825, 2017 | 101 | 2017 |
Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and double JS-K, through incorporation into PEG-protected nanoparticles V Kumar, SY Hong, AE Maciag, JE Saavedra, DH Adamson, ... Molecular pharmaceutics 7 (1), 291-298, 2010 | 100 | 2010 |
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis G Rai, AA Sayed, WA Lea, HF Luecke, H Chakrapani, S Prast-Nielsen, ... Journal of medicinal chemistry 52 (20), 6474-6483, 2009 | 99 | 2009 |
Enantioselective cyclization/hydrosilylation of 1, 6-enynes catalyzed by a cationic rhodium bis (phosphine) complex H Chakrapani, C Liu, RA Widenhoefer Organic Letters 5 (2), 157-159, 2003 | 96 | 2003 |
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh Free Radical Biology and Medicine 84, 344-354, 2015 | 91 | 2015 |
The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen Species AE Maciag, H Chakrapani, JE Saavedra, NL Morris, RJ Holland, ... Journal of Pharmacology and Experimental Therapeutics 336 (2), 313-320, 2011 | 87 | 2011 |
A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives VK Pamula, V Srinivasan, H Chakrapani, RB Fair, EJ Toone 18th IEEE International Conference on Micro Electro Mechanical Systems, 2005 …, 2005 | 77 | 2005 |
Cyclization/hydrosilylation of functionalized 1, 6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands X Wang, H Chakrapani, JW Madine, MA Keyerleber, RA Widenhoefer The Journal of organic chemistry 67 (9), 2778-2788, 2002 | 75 | 2002 |
INDQ/NO, a Bioreductively Activated Nitric Oxide Prodrug K Sharma, A Iyer, K Sengupta, H Chakrapani Organic letters 15 (11), 2636-2639, 2013 | 69 | 2013 |
A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase DS Kelkar, G Ravikumar, N Mehendale, S Singh, A Joshi, AK Sharma, ... Nature chemical biology 15 (2), 169-178, 2019 | 65 | 2019 |
Nitroreductase-activated nitric oxide (NO) prodrugs K Sharma, K Sengupta, H Chakrapani Bioorganic & medicinal chemistry letters 23 (21), 5964-5967, 2013 | 58 | 2013 |
Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs H Chakrapani, RC Kalathur, AE Maciag, ML Citro, X Ji, LK Keefer, ... Bioorganic & medicinal chemistry 16 (22), 9764-9771, 2008 | 54 | 2008 |
Reactive Oxygen Species-Triggered Tunable Hydrogen Sulfide Release P Chauhan, S Jos, H Chakrapani Organic letters 20 (13), 3766-3770, 2018 | 51 | 2018 |
Small molecule generators of biologically reactive sulfur species P Bora, P Chauhan, KA Pardeshi, H Chakrapani RSC Advances 8 (48), 27359-27374, 2018 | 48 | 2018 |
The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents AE Maciag, JE Saavedra, H Chakrapani Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009 | 46 | 2009 |
Site-directed delivery of nitric oxide to cancers K Sharma, H Chakrapani Nitric Oxide 43, 8-16, 2014 | 45 | 2014 |
Benzosultines as Sulfur Dioxide (SO2) Donors SR Malwal, M Gudem, A Hazra, H Chakrapani Organic letters 15 (5), 1116-1119, 2013 | 45 | 2013 |