| Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO2) as Antimycobacterial Agents SR Malwal, D Sriram, P Yogeeswari, VB Konkimalla, H Chakrapani Journal of medicinal chemistry 55 (1), 553-557, 2012 | 125 | 2012 |
| Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis G Rai, AA Sayed, WA Lea, HF Luecke, H Chakrapani, S Prast-Nielsen, ... Journal of medicinal chemistry 52 (20), 6474-6483, 2009 | 95 | 2009 |
| Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and double JS-K, through incorporation into PEG-protected nanoparticles V Kumar, SY Hong, AE Maciag, JE Saavedra, DH Adamson, ... Molecular pharmaceutics 7 (1), 291-298, 2010 | 85 | 2010 |
| Enantioselective cyclization/hydrosilylation of 1, 6-enynes catalyzed by a cationic rhodium bis (phosphine) complex H Chakrapani, C Liu, RA Widenhoefer Organic Letters 5 (2), 157-159, 2003 | 85 | 2003 |
| The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen Species AE Maciag, H Chakrapani, JE Saavedra, NL Morris, RJ Holland, ... Journal of Pharmacology and Experimental Therapeutics 336 (2), 313-320, 2011 | 82 | 2011 |
| Esterase Activated Carbonyl Sulfide/Hydrogen Sulfide (H2S) Donors P Chauhan, P Bora, G Ravikumar, S Jos, H Chakrapani Organic letters 19 (1), 62-65, 2017 | 77 | 2017 |
| A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives VK Pamula, V Srinivasan, H Chakrapani, RB Fair, EJ Toone 18th IEEE International Conference on Micro Electro Mechanical Systems, 2005 …, 2005 | 76 | 2005 |
| “On demand” redox buffering by H 2 S contributes to antibiotic resistance revealed by a bacteria-specific H 2 S donor P Shukla, VS Khodade, M SharathChandra, P Chauhan, S Mishra, ... Chemical science 8 (7), 4967-4972, 2017 | 74 | 2017 |
| Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh Free Radical Biology and Medicine 84, 344-354, 2015 | 74 | 2015 |
| Cyclization/hydrosilylation of functionalized 1, 6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands X Wang, H Chakrapani, JW Madine, MA Keyerleber, RA Widenhoefer The Journal of organic chemistry 67 (9), 2778-2788, 2002 | 67 | 2002 |
| INDQ/NO, a Bioreductively Activated Nitric Oxide Prodrug K Sharma, A Iyer, K Sengupta, H Chakrapani Organic letters 15 (11), 2636-2639, 2013 | 62 | 2013 |
| Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release AK Sharma, M Nair, P Chauhan, K Gupta, DK Saini, H Chakrapani Organic Letters 19 (18), 4822-4825, 2017 | 58 | 2017 |
| Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs H Chakrapani, RC Kalathur, AE Maciag, ML Citro, X Ji, LK Keefer, ... Bioorganic & medicinal chemistry 16 (22), 9764-9771, 2008 | 50 | 2008 |
| Nitroreductase-activated nitric oxide (NO) prodrugs K Sharma, K Sengupta, H Chakrapani Bioorganic & medicinal chemistry letters 23 (21), 5964-5967, 2013 | 49 | 2013 |
| A highly selective sulfinate ester probe for thiol bioimaging SR Malwal, A Labade, AS Andhalkar, K Sengupta, H Chakrapani Chemical Communications 50 (78), 11533-11535, 2014 | 40 | 2014 |
| Site-directed delivery of nitric oxide to cancers K Sharma, H Chakrapani Nitric Oxide 43, 8-16, 2014 | 39 | 2014 |
| Bioreductively Activated Reactive Oxygen Species (ROS) Generators as MRSA Inhibitors V Khodade, M Sharath Chandra, A Banerjee, S Lahiri, M Pulipeta, ... ACS Medicinal Chemistry Letters, 2014 | 39 | 2014 |
| The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents AE Maciag, JE Saavedra, H Chakrapani Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009 | 39 | 2009 |
| Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound H Chakrapani, TC Wilde, ML Citro, MM Goodblatt, LK Keefer, ... Bioorganic & medicinal chemistry 16 (5), 2657-2664, 2008 | 37 | 2008 |
| V-PROLI/NO, a prodrug of the nitric oxide donor, PROLI/NO H Chakrapani, BM Showalter, L Kong, LK Keefer, JE Saavedra Organic Letters 9 (17), 3409-3412, 2007 | 36 | 2007 |
