Venkat R Chirasani
Venkat R Chirasani
R.L. Juliano Structural Bioinformatics Core, UNC-Chapel Hill
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Modulation of the mitochondrial voltage dependent anion channel (VDAC) by curcumin
D Tewari, T Ahmed, VR Chirasani, PK Singh, SK Maji, S Senapati, ...
Biochimica Et Biophysica Acta (BBA)-Biomembranes 1848 (1), 151-158, 2015
Catestatin Gly364Ser variant alters systemic blood pressure and the risk for hypertension in human populations via endothelial nitric oxide pathway
M Kiranmayi, VR Chirasani, PKR Allu, L Subramanian, EE Martelli, ...
Hypertension 68 (2), 334-347, 2016
Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice
JA Dominguez Rieg, VR Chirasani, H Koepsell, S Senapati, SK Mahata, ...
Laboratory Investigation 96 (1), 98-111, 2016
Modifications to the framework regions eliminate chimeric antigen receptor tonic signaling
E Landoni, G Fucá, J Wang, VR Chirasani, Z Yao, E Dukhovlinova, ...
Cancer immunology research 9 (4), 441-453, 2021
Structural plasticity of cholesteryl ester transfer protein assists the lipid transfer activity
VR Chirasani, PD Revanasiddappa, S Senapati
Journal of Biological Chemistry 291 (37), 19462-19473, 2016
Two-input protein logic gate for computation in living cells
YL Vishweshwaraiah, J Chen, VR Chirasani, ED Tabdanov, ...
Nature communications 12 (1), 6615, 2021
Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel
L Xu, VR Chirasani, JS Carter, DA Pasek, NV Dokholyan, N Yamaguchi, ...
Journal of Biological Chemistry 293 (50), 19501-19509, 2018
Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation
PKR Allu, VR Chirasani, D Ghosh, A Mani, AK Bera, SK Maji, S Senapati, ...
Journal of Biological Chemistry 289 (7), 4455-4469, 2014
Molecular analyses of novel ASAH1 mutations causing Farber lipogranulomatosis: analyses of exonic splicing enhancer inactivating mutation
MD Bashyam, AK Chaudhary, M Kiran, V Reddy, HA Nagarajaram, ...
Clinical genetics 86 (6), 530-538, 2014
A founder ectodysplasin A receptor (EDAR) mutation results in a high frequency of the autosomal recessive form of hypohidrotic ectodermal dysplasia in India
MD Bashyam, AK Chaudhary, EC Reddy, V Reddy, V Acharya, ...
British journal of dermatology 166 (4), 819-829, 2012
Development of a novel multi-isoform ALDH inhibitor effective as an antimelanoma agent
SS Dinavahi, R Gowda, K Gowda, CG Bazewicz, VR Chirasani, MB Battu, ...
Molecular cancer therapeutics 19 (2), 447-459, 2020
Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins
S Bonfanti, MC Lionetti, MR Fumagalli, VR Chirasani, G Tiana, ...
Scientific reports 9 (1), 7615, 2019
A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation
VR Chirasani, L Xu, HG Addis, DA Pasek, NV Dokholyan, G Meissner, ...
American Journal of Physiology-Cell Physiology 317 (2), C358-C365, 2019
Divergent mechanisms activating RAS and small GTPases through post-translational modification
N Osaka, Y Hirota, D Ito, Y Ikeda, R Kamata, Y Fujii, VR Chirasani, ...
Frontiers in Molecular Biosciences 8, 707439, 2021
Molecular Basis of Differential Stability and Temperature Sensitivity of ZIKA versus Dengue Virus Protein Shells
C Pindi, VR Chirasani, MH Rahman, M Ahsan, PD Revanasiddappa, ...
Scientific Reports 10 (1), 8411, 2020
Limits in Accuracy and a Strategy of RNA Structure Prediction Using Experimental Information
J Wang, B Williams, VR Chirasani, A Krokhotin, R Das, ...
Nucleic Acids Research 47 (11), 5563–5572, 2019
Mechanism of inhibition of cholesteryl ester transfer protein by small molecule inhibitors
VR Chirasani, R Sankar, S Senapati
The Journal of Physical Chemistry B 120 (33), 8254-8263, 2016
Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation
BM Murphy, EM Terrell, VR Chirasani, TJ Weiss, RE Lew, ...
Nature Communications 13 (1), 3153, 2022
Structural and functional interactions between the Ca2+-, ATP-, and caffeine-binding sites of skeletal muscle ryanodine receptor (RyR1)
VR Chirasani, DA Pasek, G Meissner
Journal of Biological Chemistry 297 (3), 2021
Decrease in the generation of amyloid-β due to salvianolic acid B by modulating BACE1 activity
S Sundara Kumar Durairajan, V Reddy Chirasani, ...
Current Alzheimer Research 14 (11), 1229-1237, 2017
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