Mohane Coumar S
Mohane Coumar S
Assistant Professor, Centre for Bioinformatics, Pondicherry University
Verified email at - Homepage
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Treat cancers by targeting survivin: just a dream or future reality?
MS Coumar, FY Tsai, JR Kanwar, S Sarvagalla, CHA Cheung
Cancer treatment reviews 39 (7), 802-811, 2013
Anti-influenza drug discovery: structure− activity relationship and mechanistic insight into novel angelicin derivatives
JY Yeh, MS Coumar, JT Horng, HY Shiao, FM Kuo, HL Lee, IC Chen, ...
Journal of medicinal chemistry 53 (4), 1519-1533, 2010
Aurora kinase inhibitors in preclinical and clinical testing
CHA Cheung, MS Coumar, HP Hsieh, JY Chang
Expert opinion on investigational drugs 18 (4), 379-398, 2009
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach
YS Wu, MS Coumar, JY Chang, HY Sun, FM Kuo, CC Kuo, YJ Chen, ...
Journal of medicinal chemistry 52 (15), 4941-4945, 2009
Design and Synthesis of Tetrahydropyridothieno[2,3-d]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side …
CH Wu, MS Coumar, CY Chu, WH Lin, YR Chen, CT Chen, HY Shiao, ...
Journal of medicinal chemistry 53 (20), 7316-7326, 2010
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers
CHA Cheung, HH Chen, CC Kuo, CY Chang, MS Coumar, HP Hsieh, ...
Molecular cancer 8 (1), 1-15, 2009
Scaffold-hopping strategy: synthesis and biological evaluation of 5, 6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
YS Tung, MS Coumar, YS Wu, HY Shiao, JY Chang, JP Liou, P Shukla, ...
Journal of medicinal chemistry 54 (8), 3076-3080, 2011
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors
YH Peng, HY Shiao, CH Tu, PM Liu, JTA Hsu, PK Amancha, JS Wu, ...
Journal of medicinal chemistry 56 (10), 3889-3903, 2013
Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity
MS Coumar, JS Leou, P Shukla, JS Wu, AK Dixit, WH Lin, CY Chang, ...
Journal of medicinal chemistry 52 (4), 1050-1062, 2009
Evolutionary algorithms for de novo drug design–A survey
RV Devi, SS Sathya, MS Coumar
Applied Soft Computing 27, 543-552, 2015
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer
SB Syed, H Arya, IH Fu, TK Yeh, L Periyasamy, HP Hsieh, MS Coumar
Scientific reports 7 (1), 1-18, 2017
Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification
MS Coumar, CY Chu, CW Lin, HY Shiao, YL Ho, R Reddy, WH Lin, ...
Journal of medicinal chemistry 53 (13), 4980-4988, 2010
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity
YK Chiang, CC Kuo, YS Wu, CT Chen, MS Coumar, JS Wu, HP Hsieh, ...
Journal of medicinal chemistry 52 (14), 4221-4233, 2009
Aurora kinase inhibitor patents and agents in clinical testing: an update (2011–2013)
CHA Cheung, S Sarvagalla, JYC Lee, YC Huang, MS Coumar
Expert opinion on therapeutic patents 24 (9), 1021-1038, 2014
Aurora kinase inhibitor patents and agents in clinical testing: an update (2009–10) This article is an update to aurora kinase inhibitors review, which appeared in: Expert Opin …
CHA Cheung, MS Coumar, JY Chang, HP Hsieh
Expert opinion on therapeutic patents 21 (6), 857-884, 2011
Characterization of a new rat urinary metabolite of piperine by LC/NMR/MS studies
S Bajad, M Coumar, R Khajuria, OP Suri, KL Bedi
European journal of pharmaceutical sciences 19 (5), 413-421, 2003
Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin–an in vitro and in silico approach
K Mohankumar, S Pajaniradje, S Sridharan, VK Singh, L Ronsard, ...
Chemico-biological interactions 210, 51-63, 2014
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification
YY Ke, VK Singh, MS Coumar, YC Hsu, WC Wang, JS Song, CH Chen, ...
Scientific reports 5 (1), 1-12, 2015
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
JM Wu, CT Chen, MS Coumar, WH Lin, ZJ Chen, JTA Hsu, YH Peng, ...
Proceedings of the National Academy of Sciences 110 (19), E1779-E1787, 2013
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine Aurora kinase inhibitor
HY Shiao, MS Coumar, CW Chang, YY Ke, YH Chi, CY Chu, HY Sun, ...
Journal of medicinal chemistry 56 (13), 5247-5260, 2013
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