| Treat cancers by targeting survivin: just a dream or future reality? MS Coumar, FY Tsai, JR Kanwar, S Sarvagalla, CHA Cheung Cancer treatment reviews 39 (7), 802-811, 2013 | 189 | 2013 |
| Anti-influenza drug discovery: structure− activity relationship and mechanistic insight into novel angelicin derivatives JY Yeh, MS Coumar, JT Horng, HY Shiao, FM Kuo, HL Lee, IC Chen, ... Journal of medicinal chemistry 53 (4), 1519-1533, 2010 | 175 | 2010 |
| Evolutionary algorithms for de novo drug design–A survey RV Devi, SS Sathya, MS Coumar Applied Soft Computing 27, 543-552, 2015 | 137 | 2015 |
| Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors YH Peng, HY Shiao, CH Tu, PM Liu, JTA Hsu, PK Amancha, JS Wu, ... Journal of medicinal chemistry 56 (10), 3889-3903, 2013 | 125 | 2013 |
| Aurora kinase inhibitors in preclinical and clinical testing CHA Cheung, MS Coumar, HP Hsieh, JY Chang Expert opinion on investigational drugs 18 (4), 379-398, 2009 | 116 | 2009 |
| Design and Synthesis of Tetrahydropyridothieno[2,3-d]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side … CH Wu, MS Coumar, CY Chu, WH Lin, YR Chen, CT Chen, HY Shiao, ... Journal of medicinal chemistry 53 (20), 7316-7326, 2010 | 114 | 2010 |
| BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells TY Lin, HH Chan, SH Chen, S Sarvagalla, PS Chen, MS Coumar, ... Autophagy 16 (7), 1296-1313, 2020 | 105 | 2020 |
| Scaffold-hopping strategy: synthesis and biological evaluation of 5, 6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents YS Tung, MS Coumar, YS Wu, HY Shiao, JY Chang, JP Liou, P Shukla, ... Journal of medicinal chemistry 54 (8), 3076-3080, 2011 | 102 | 2011 |
| Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer SB Syed, H Arya, IH Fu, TK Yeh, L Periyasamy, HP Hsieh, MS Coumar Scientific reports 7 (1), 7972, 2017 | 101 | 2017 |
| Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach YS Wu, MS Coumar, JY Chang, HY Sun, FM Kuo, CC Kuo, YJ Chen, ... Journal of medicinal chemistry 52 (15), 4941-4945, 2009 | 101 | 2009 |
| Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers CHA Cheung, HH Chen, CC Kuo, CY Chang, MS Coumar, HP Hsieh, ... Molecular cancer 8, 1-15, 2009 | 92 | 2009 |
| Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity MS Coumar, JS Leou, P Shukla, JS Wu, AK Dixit, WH Lin, CY Chang, ... Journal of medicinal chemistry 52 (4), 1050-1062, 2009 | 86 | 2009 |
| Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification YY Ke, VK Singh, MS Coumar, YC Hsu, WC Wang, JS Song, CH Chen, ... Scientific reports 5 (1), 11702, 2015 | 77 | 2015 |
| Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification MS Coumar, CY Chu, CW Lin, HY Shiao, YL Ho, R Reddy, WH Lin, ... Journal of medicinal chemistry 53 (13), 4980-4988, 2010 | 74 | 2010 |
| Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity YK Chiang, CC Kuo, YS Wu, CT Chen, MS Coumar, JS Wu, HP Hsieh, ... Journal of medicinal chemistry 52 (14), 4221-4233, 2009 | 71 | 2009 |
| Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin–an in vitro and in silico approach K Mohankumar, S Pajaniradje, S Sridharan, VK Singh, L Ronsard, ... Chemico-biological interactions 210, 51-63, 2014 | 63 | 2014 |
| Aurora kinase inhibitor patents and agents in clinical testing: an update (2011–2013) CHA Cheung, S Sarvagalla, JYC Lee, YC Huang, MS Coumar Expert opinion on therapeutic patents 24 (9), 1021-1038, 2014 | 61 | 2014 |
| Aurora kinase inhibitor patents and agents in clinical testing: an update (2009–10) This article is an update to aurora kinase inhibitors review, which appeared in: Expert Opin … CHA Cheung, MS Coumar, JY Chang, HP Hsieh Expert opinion on therapeutic patents 21 (6), 857-884, 2011 | 60 | 2011 |
| Characterization of a new rat urinary metabolite of piperine by LC/NMR/MS studies S Bajad, M Coumar, R Khajuria, OP Suri, KL Bedi European journal of pharmaceutical sciences 19 (5), 413-421, 2003 | 59 | 2003 |
| Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules JM Wu, CT Chen, MS Coumar, WH Lin, ZJ Chen, JTA Hsu, YH Peng, ... Proceedings of the National Academy of Sciences 110 (19), E1779-E1787, 2013 | 54 | 2013 |
Hsing-Pang HsiehNational Health Research InstitutesVerified email at nhri.org.tw
