In vitro and in vivo antitumor activity of platinum (II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N (4 … D Kovala-Demertzi, A Papageorgiou, L Papathanasis, A Alexandratos, ... European journal of medicinal chemistry 44 (3), 1296-1302, 2009 | 97 | 2009 |
Synthesis, characterization, crystal structures, in vitro and in vivo antitumor activity of palladium (II) and zinc (II) complexes with 2-formyl and 2-acetyl pyridine N (4)-1 … D Kovala-Demertzi, A Alexandratos, A Papageorgiou, PN Yadav, ... Polyhedron 27 (13), 2731-2738, 2008 | 82 | 2008 |
Synthesis and anticancer activity of novel 3, 6-disubstituted 1, 2, 4-triazolo-[3, 4-b]-1, 3, 4-thiadiazole derivatives G Charitos, DT Trafalis, P Dalezis, C Potamitis, V Sarli, P Zoumpoulakis, ... Arabian Journal of Chemistry 12 (8), 4784-4794, 2019 | 54 | 2019 |
Synthesis and biological evaluation of a Platinum (II)-c (RGDyK) conjugate for integrin-targeted photodynamic therapy T Chatzisideri, S Thysiadis, S Katsamakas, P Dalezis, I Sigala, ... European Journal of Medicinal Chemistry 141, 221-231, 2017 | 50 | 2017 |
Synthesis and evaluation of new steroidal lactam conjugates with aniline mustards as potential antileukemic therapeutics D Trafalis, E Geromichalou, P Dalezis, N Nikoleousakos, V Sarli Steroids 115, 1-8, 2016 | 26 | 2016 |
Novel c (RGDyK)-based conjugates of POPAM and 5-fluorouracil for integrin-targeted cancer therapy S Thysiadis, S Katsamakas, P Dalezis, T Chatzisideri, D Trafalis, V Sarli Future medicinal chemistry 9 (18), 2181-2196, 2017 | 17 | 2017 |
Antitumour effect of a-and d-lactam androgen nitrogen mustards on non-small cell lung carcinoma DT Trafalis, C Camoutsis, P Dalezis, A Papageorgiou, M Kontos, ... JOURNAL-BALKAN UNION OF ONCOLOGY 9, 275-282, 2004 | 17 | 2004 |
Silver complexes with heterocyclic thioamide and tertiary arylphosphane ligands: Synthesis, crystal structures, in vitro and in silico antibacterial and cytotoxic activity, and … D Anastasiadou, E Geromichalou, E Tsavea, G Psomas, ... Journal of Inorganic Biochemistry 210, 111167, 2020 | 13 | 2020 |
Preclinical studies on NSC290205 aza‐steroid alkylator activity in combination with adriamycin against lymphoid leukaemia DTP Trafalis, D Tsavdaridis, C Camoutsis, V Karayiani, D Mourelatos, ... British journal of haematology 128 (3), 343-350, 2005 | 11 | 2005 |
Dexamethasone plus octreotide regimen increases anticancer effects of docetaxel on TRAMP-C1 prostate cancer model P Dalezis, GD Geromichalos, DT Trafalis, N Pissimissis, ... in vivo 26 (1), 75-86, 2012 | 10 | 2012 |
In silico study of potential antiviral activity of copper (II) complexes with non–steroidal anti–inflammatory drugs on various SARS–CoV–2 target proteins EG Geromichalou, DT Trafalis, P Dalezis, G Malis, G Psomas, ... Journal of Inorganic Biochemistry 231, 111805, 2022 | 9 | 2022 |
Antitumor activity of crocin, crocetin and safranal on murine P388 leukemia bearing mice P Dalezis, E Papageorgiou, E Geromichalou, G Geromichalus 3rd International symposium on saffron Forthcoming challenges in cultivation …, 2009 | 9 | 2009 |
In silico/in vitro study of hybrid D-modified steroidal alkylator anticancer activity using uridine phosphorylase as target protein GD Geromichalos, E Geromichalou, C Camoutsis, M Kontos, P Dalezis, ... Anticancer research 31 (3), 831-842, 2011 | 8 | 2011 |
Synthesis and biological activity of bisindole derivatives as novel MARK4 inhibitors M Voura, S Anwar, S Thysiadis, P Κhan, P Dalezis, DT Trafalis, MI Hassan, ... European Journal of Medicinal Chemistry Reports 6, 100076, 2022 | 7 | 2022 |
Silver (i) complexes bearing heterocyclic thioamide ligands with NH 2 and CF 3 substituents: effect of ligand group substitution on antibacterial and anticancer properties D Varna, E Geromichalou, AG Hatzidimitriou, R Papi, G Psomas, ... Dalton Transactions 51 (24), 9412-9431, 2022 | 7 | 2022 |
8-Hydroxy-2’-Deoxyguanosine and 8-nitroguanine production and detection in blood serum of breast cancer patients in response to postoperative complementary external ionizing … KE Verigos, S Sagredou, K Orfanakos, P Dalezis, DT Trafalis Dose-Response 18 (4), 1559325820982172, 2020 | 6 | 2020 |
Discovery of steroidal lactam conjugates of POPAM-NH2 with potent anticancer activity D Trafalis, P Dalezis, E Geromichalou, S Sagredou, E Sflakidou, M Voura, ... Future Medicinal Chemistry 12 (1), 19-35, 2020 | 6 | 2020 |
Targeting on poly (ADP‐ribose) polymerase activity with DNA‐damaging hybrid lactam‐steroid alkylators in wild‐type and BRCA1‐mutated ovarian cancer cells DT Trafalis, A Polonifi, P Dalezis, N Nikoleousakos, S Katsamakas, V Sarli Chemical Biology & Drug Design 90 (5), 854-866, 2017 | 6 | 2017 |
Positive urinary cytology in patients with lung cancer in the absence of obvious urine tract metastases E Voulgaris, G Pentheroudakis, L Pappa, M Bafa, A Goussia, P Dalezis, ... Lung cancer 73 (1), 51-58, 2011 | 6 | 2011 |
A preclinical survey on the efficacy of lactandrate in the treatment of colon carcinoma DT Trafalis, GD Geromichalos, N Bountouroglou, D Koumbi, M Kontos, ... J BUON 10 (2), 227-234, 2005 | 6 | 2005 |