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Prof Damian Mole
Prof Damian Mole
1777 Chair of Surgery, MRC Senior Clinical Fellow and Honorary Consultant Surgeon, Edinburgh
Verified email at ed.ac.uk - Homepage
Title
Cited by
Cited by
Year
Resolving the fibrotic niche of human liver cirrhosis at single-cell level
P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, ...
Nature 575 (7783), 512-518, 2019
10202019
Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis
R Dobie, JR Wilson-Kanamori, BEP Henderson, JR Smith, KP Matchett, ...
Cell reports 29 (7), 1832-1847. e8, 2019
2812019
Management of liver trauma
SA Badger, R Barclay, P Campbell, DJ Mole, T Diamond
World journal of surgery 33, 2522-2537, 2009
2052009
Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis
R Duffin, RA O’Connor, S Crittenden, T Forster, C Yu, X Zheng, D Smyth, ...
Science 351 (6279), 1333-1338, 2016
1672016
Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis
DJ Mole, SP Webster, I Uings, X Zheng, M Binnie, K Wilson, ...
Nature medicine 22 (2), 202-209, 2016
1442016
Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records
DJ Mole, B Olabi, V Robinson, OJ Garden, RW Parks
Hpb 11 (2), 166-170, 2009
1312009
Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo
JA Fallowfield, AL Hayden, VK Snowdon, RL Aucott, BM Stutchfield, ...
Hepatology 59 (4), 1492-1504, 2014
1062014
The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis
JE Fishman, G Levy, V Alli, X Zheng, DJ Mole, EA Deitch
Shock 42 (3), 264-270, 2014
902014
Detailed fluid resuscitation profiles in patients with severe acute pancreatitis
DJ Mole, A Hall, D McKeown, OJ Garden, RW Parks
Hpb 13 (1), 51-58, 2011
702011
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: a rationale for safer glucocorticoid replacement therapy
M Nixon, SD Mackenzie, AI Taylor, NZM Homer, DE Livingstone, ...
Science Translational Medicine 8 (352), 352ra109-352ra109, 2016
632016
Stromal cells covering omental fat-associated lymphoid clusters trigger formation of neutrophil aggregates to capture peritoneal contaminants
LH Jackson-Jones, P Smith, JR Portman, MS Magalhaes, KJ Mylonas, ...
Immunity 52 (4), 700-715. e6, 2020
622020
Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the …
CM Bunce, JC Mountford, PJ French, DJ Mole, J Durham, RH Michell, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1311 (3), 189-198, 1996
531996
Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct
RH Stimson, AJ Anderson, LE Ramage, DP Macfarlane, AC de Beaux, ...
Diabetes, Obesity and Metabolism 19 (6), 883-891, 2017
502017
Tryptophan catabolites in mesenteric lymph may contribute to pancreatitis-associated organ failure
DJ Mole, NV McFerran, G Collett, C O'Neill, T Diamond, OJ Garden, ...
Journal of British Surgery 95 (7), 855-867, 2008
482008
Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
S Crittenden, M Goepp, J Pollock, CT Robb, DJ Smyth, Y Zhou, ...
Science advances 7 (7), eabd7954, 2021
462021
Pre-, peri-and post-operative factors for the development of pancreatic fistula after pancreatic surgery
K Søreide, AJ Healey, DJ Mole, RW Parks
Hpb 21 (12), 1621-1631, 2019
452019
Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury
X Zheng, A Zhang, M Binnie, K McGuire, SP Webster, J Hughes, ...
Experimental & Molecular Medicine 51 (2), 1-14, 2019
432019
Lead discovery for human kynurenine 3-monooxygenase by high-throughput RapidFire mass spectrometry
DM Lowe, M Gee, C Haslam, B Leavens, E Christodoulou, P Hissey, ...
Journal of biomolecular screening 19 (4), 508-515, 2014
432014
Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase
JP Hutchinson, P Rowland, MRD Taylor, EM Christodoulou, C Haslam, ...
Nature Communications 8 (1), 15827, 2017
402017
The isolated perfused liver response to a ‘second hit’of portal endotoxin during severe acute pancreatitis
DJ Mole, MA Taylor, NV McFerran, T Diamond
Pancreatology 5 (4-5), 475-485, 2005
402005
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