Synthesis and tumor inhibitory activity of novel coumarin analogues targeting angiogenesis and apoptosis SAK B.R. Vijay Avina, Prabhu Thirusangua, , V. Lakshmi European Journal of medicinal Chemistry, 2014 | 120 | 2014 |
Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-κB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cδ AM Bair, PB Thippegowda, M Freichel, N Cheng, DY Richard, SM Vogel, ... Journal of Biological Chemistry 284 (1), 563-574, 2009 | 96 | 2009 |
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation C Tiruppathi, D Soni, DM Wang, J Xue, V Singh, PB Thippegowda, ... Nature immunology 15 (3), 239-247, 2014 | 87 | 2014 |
NF-κB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-κB site in the ICAM-1 gene J Xue, PB Thippegowda, G Hu, K Bachmaier, JW Christman, AB Malik, ... Physiological genomics 38 (1), 42-53, 2009 | 72 | 2009 |
Evaluation of serum vascular endothelial growth factor (VEGF) and microvessel density (MVD) as prognostic indicators in carcinoma breast S Shivakumar, BT Prabhakar, K Jayashree, MGR Rajan, BP Salimath Journal of cancer research and clinical oncology 135, 627-636, 2009 | 70 | 2009 |
Anti-tumor and proapoptotic effect of novel synthetic benzophenone analogues in Ehrlich ascites tumor cells BT Prabhakar, SA Khanum, K Jayashree, BP Salimath, S Shashikanth Bioorganic & medicinal chemistry 14 (2), 435-446, 2006 | 70 | 2006 |
Antioxidant potentials in sprouts vs. seeds of Vigna radiata and Macrotyloma uniflorum CK Ramesh, A Rehman, BT Prabhakar, VA BR, AR SJ Journal of Applied Pharmaceutical Science 1 (07), 99-103, 2011 | 62 | 2011 |
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors SAK T. Prashantha, Prabhu Thirusangu, B.R. Vijay Avin, V. Lakshmi Ranganatha ... European Journal of Medicinal Chemistry 87, 274-283, 2014 | 54 | 2014 |
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation P Thirusangu, V Vigneshwaran, T Prashanth, BR Vijay Avin, VH Malojirao, ... Angiogenesis 20, 55-71, 2017 | 52 | 2017 |
Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs VL Ranganatha, BRV Avin, P Thirusangu, T Prashanth, BT Prabhakar, ... Life sciences 93 (23), 904-911, 2013 | 52 | 2013 |
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma T Prashanth, BRV Avin, P Thirusangu, VL Ranganatha, BT Prabhakar, ... Biomedicine & Pharmacotherapy 112, 108707, 2019 | 48 | 2019 |
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression P Thirusangu, V Vigneshwaran, VL Ranganatha, BRV Avin, SA Khanum, ... Biochemical pharmacology 125, 26-40, 2017 | 46 | 2017 |
Synthesis of oxadiazole–morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton’s Lymphoma M Al-Ghorbani, V Vigneshwaran, VL Ranganatha, BT Prabhakar, ... Bioorganic Chemistry 60, 136-146, 2015 | 46 | 2015 |
Anthelmintic and antimicrobial activities in some species of mulberry AR Sj, R Mahmood Int J Pharm Pharm Sci 4, 335-8, 2012 | 45 | 2012 |
Inhibition of HIF-1α activity by BP-1 ameliorates adjuvant induced arthritis in rats J Shankar, PB Thippegowda, SA Kanum Biochemical and biophysical research communications 387 (2), 223-228, 2009 | 45 | 2009 |
Antiangiogenic effect of 2-benzoyl–phenoxy acetamide in EAT cell is mediated by HIF-1α and down regulation of VEGF of in-vivo BT Prabhakar, SA Khanum, S Shashikanth, BP Salimath Investigational new drugs 24, 471-478, 2006 | 45 | 2006 |
Ca2+ influx via TRPC channels induces NF-κB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells PB Thippegowda, V Singh, PC Sundivakkam, J Xue, AB Malik, ... American Journal of Physiology-Cell Physiology 298 (3), C656-C664, 2010 | 40 | 2010 |
DAO-9 (2, 5-di (4-aryloylaryloxymethyl)-1, 3, 4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma HD Gurupadaswamy, P Thirusangu, BRV Avin, V Vigneshwaran, ... Biomedicine & Pharmacotherapy 68 (6), 791-797, 2014 | 39 | 2014 |
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton’s lymphoma M Al-Ghorbani, P Thirusangu, HD Gurupadaswamy, V Girish, ... Bioorganic chemistry 65, 73-81, 2016 | 38 | 2016 |
New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression. ABR Vijay, T Prabhu, CK Ramesh, V Vigneshwaran, M Riaz, K Jayashree, ... Biochemical and biophysical research communications 448 (2), 139-144, 2014 | 38 | 2014 |