Follow
Dinesh Gautam
Dinesh Gautam
Pharmacologist, FDA
Verified email at fda.hhs.gov
Title
Cited by
Cited by
Year
Role of brain insulin receptor in control of body weight and reproduction
JC Bruning, D Gautam, DJ Burks, J Gillette, M Schubert, PC Orban, ...
Science 289 (5487), 2122-2125, 2000
27012000
Role for neuronal insulin resistance in neurodegenerative diseases
M Schubert, D Gautam, D Surjo, K Ueki, S Baudler, D Schubert, T Kondo, ...
Proceedings of the National Academy of Sciences 101 (9), 3100-3105, 2004
7482004
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
J Wess, RM Eglen, D Gautam
Nature reviews Drug discovery 6 (9), 721-733, 2007
7242007
Muscarinic acetylcholine receptors: novel opportunities for drug development
AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess
Nature reviews Drug discovery 13 (7), 549-560, 2014
4282014
A chemical-genetic approach to study G protein regulation of β cell function in vivo
JM Guettier, D Gautam, M Scarselli, IR de Azua, JH Li, E Rosemond, X Ma, ...
Proceedings of the National Academy of Sciences 106 (45), 19197-19202, 2009
3802009
A critical role for β cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
D Gautam, SJ Han, FF Hamdan, J Jeon, B Li, JH Li, Y Cui, D Mears, H Lu, ...
Cell metabolism 3 (6), 449-461, 2006
3392006
Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M3 Muscarinic Acetylcholine Receptor–Deficient Mice
A Duttaroy, CL Zimliki, D Gautam, Y Cui, D Mears, J Wess
Diabetes 53 (7), 1714-1720, 2004
2482004
Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single-and double-knockout mice
D Gautam, TS Heard, Y Cui, G Miller, L Bloodworth, J Wess
Molecular Pharmacology 66 (2), 260-267, 2004
1822004
Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance
M Röhl, M Pasparakis, S Baudler, J Baumgartl, D Gautam, M Huth, ...
The Journal of clinical investigation 113 (3), 474-481, 2004
1432004
Beneficial metabolic effects of M3 muscarinic acetylcholine receptor deficiency
D Gautam, O Gavrilova, J Jeon, S Pack, W Jou, Y Cui, JH Li, J Wess
Cell metabolism 4 (5), 363-375, 2006
1122006
RGS4 is a negative regulator of insulin release from pancreatic β-cells in vitro and in vivo
I Ruiz de Azua, M Scarselli, E Rosemond, D Gautam, W Jou, O Gavrilova, ...
Proceedings of the National Academy of Sciences 107 (17), 7999-8004, 2010
1062010
Role of the M3 muscarinic acetylcholine receptor in β‐cell function and glucose homeostasis
D Gautam, SJ Han, A Duttaroy, D Mears, FF Hamdan, JH Li, Y Cui, J Jeon, ...
Diabetes, Obesity and Metabolism 9, 158-169, 2007
962007
A Novel Experimental Strategy to Assess the Metabolic Effects of Selective Activation of a Gq-Coupled Receptor in Hepatocytes In Vivo
J Hua Li, S Jain, SM McMillin, Y Cui, D Gautam, W Sakamoto, H Lu, ...
Endocrinology 154 (10), 3539-3551, 2013
692013
Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications
IR de Azua, D Gautam, JM Guettier, J Wess
Trends in endocrinology & metabolism 22 (2), 74-80, 2011
672011
Muscarinic acetylcholine receptor knockout mice show distinct synaptic plasticity impairments in the visual cortex
N Origlia, N Kuczewski, E Aztiria, D Gautam, J Wess, L Domenici
The Journal of physiology 577 (3), 829-840, 2006
672006
Metabolic Roles of the M3 Muscarinic Acetylcholine Receptor Studied with M3 Receptor Mutant Mice: A Review
D Gautam, J Jeon, JH Li, SJ Han, FF Hamdan, Y Cui, H Lu, C Deng, ...
Journal of Receptors and Signal Transduction 28 (1-2), 93-108, 2008
662008
Cholinergic stimulation of amylase secretion from pancreatic acinar cells studied with muscarinic acetylcholine receptor mutant mice
D Gautam, SJ Han, TS Heard, Y Cui, G Miller, L Bloodworth, J Wess
Journal of Pharmacology and Experimental Therapeutics 313 (3), 995-1002, 2005
652005
Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses
MC Wright, S Potluri, X Wang, E Dentcheva, D Gautam, A Tessler, J Wess, ...
Journal of Neuroscience 29 (47), 14942-14955, 2009
632009
Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice
JH Li, D Gautam, SJ Han, JM Guettier, Y Cui, H Lu, C Deng, J O'Hare, ...
Diabetes 58 (12), 2776-2787, 2009
622009
Beneficial Metabolic Effects Caused by Persistent Activation of β-Cell M3 Muscarinic Acetylcholine Receptors in Transgenic Mice
D Gautam, IR de Azua, JH Li, JM Guettier, T Heard, Y Cui, H Lu, W Jou, ...
Endocrinology 151 (11), 5185-5194, 2010
542010
The system can't perform the operation now. Try again later.
Articles 1–20