| Silibinin efficacy against human hepatocellular carcinoma L Varghese, C Agarwal, A Tyagi, RP Singh, R Agarwal Clinical cancer research 11 (23), 8441-8448, 2005 | 208 | 2005 |
| Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI–CDK–cyclin cascade, and caspase 3 and PARP cleavages A Tyagi, C Agarwal, G Harrison, LM Glode, R Agarwal Carcinogenesis 25 (9), 1711-1720, 2004 | 200 | 2004 |
| Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in … A Tyagi, R Agarwal, C Agarwal Oncogene 22 (9), 1302-1316, 2003 | 189 | 2003 |
| Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR–Chk1/2–Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells A Tyagi, RP Singh, C Agarwal, S Siriwardana, RA Sclafani, R Agarwal Carcinogenesis 26 (11), 1978-1987, 2005 | 180 | 2005 |
| Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma … C Agarwal, A Tyagi, R Agarwal Molecular cancer therapeutics 5 (12), 3294-3302, 2006 | 173 | 2006 |
| Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells C Agarwal, A Tyagi, M Kaur, R Agarwal Carcinogenesis 28 (7), 1463-1470, 2007 | 169 | 2007 |
| Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-κB and signal transducers and … A Tyagi, RP Singh, K Ramasamy, K Raina, EF Redente, LD Dwyer-Nield, ... Cancer Prevention Research 2 (1), 74-83, 2009 | 147 | 2009 |
| Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of β-catenin-dependent signaling M Kaur, B Velmurugan, A Tyagi, C Agarwal, RP Singh, R Agarwal Neoplasia 12 (5), 415-424, 2010 | 131 | 2010 |
| Silibinin inhibits human nonsmall cell lung cancer cell growth through cell‐cycle arrest by modulating expression and function of key cell‐cycle regulators S Mateen, A Tyagi, C Agarwal, RP Singh, R Agarwal Molecular Carcinogenesis: Published in cooperation with the University of …, 2010 | 128 | 2010 |
| Oral Silibinin Inhibits In vivo Human Bladder Tumor Xenograft Growth Involving Down-Regulation of Survivin RP Singh, A Tyagi, G Sharma, S Mohan, R Agarwal Clinical Cancer Research 14 (1), 300-308, 2008 | 125 | 2008 |
| Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells A Tyagi, N Bhatia, MS Condon, MC Bosland, C Agarwal, R Agarwal The Prostate 53 (3), 211-217, 2002 | 125 | 2002 |
| Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for … A Tyagi, RP Singh, C Agarwal, R Agarwal Carcinogenesis 27 (11), 2269-2280, 2006 | 120 | 2006 |
| Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft M Kaur, B Velmurugan, A Tyagi, G Deep, S Katiyar, C Agarwal, R Agarwal Molecular cancer therapeutics 8 (8), 2366-2374, 2009 | 111 | 2009 |
| Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate … A Tyagi, C Agarwal, R Agarwal Molecular cancer therapeutics 1 (7), 525-532, 2002 | 99 | 2002 |
| Resveratrol Selectively Induces DNA Damage, Independent of Smad4 Expression, in Its Efficacy against Human Head and Neck Squamous Cell Carcinoma A Tyagi, M Gu, T Takahata, B Frederick, C Agarwal, S Siriwardana, ... Clinical Cancer Research 17 (16), 5402-5411, 2011 | 93 | 2011 |
| Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine–induced urinary bladder carcinogenesis in male ICR mice A Tyagi, K Raina, RP Singh, M Gu, C Agarwal, G Harrison, LM Glode, ... Molecular cancer therapeutics 6 (12), 3248-3255, 2007 | 85 | 2007 |
| SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain A Tyagi, CU Nguyen, T Chong, CR Michel, KS Fritz, N Reisdorph, ... Scientific reports 8 (1), 17547, 2018 | 83 | 2018 |
| Silibinin modulates TNF‐α and IFN‐γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells A Tyagi, C Agarwal, LD Dwyer‐Nield, RP Singh, AM Malkinson, ... Molecular carcinogenesis 51 (10), 832-842, 2012 | 81 | 2012 |
| Silibinin Prevents Lung Tumorigenesis in Wild-Type but not in iNOS−/− Mice: Potential of Real-Time Micro-CT in Lung Cancer Chemoprevention Studies K Ramasamy, LD Dwyer-Nield, NJ Serkova, KM Hasebroock, A Tyagi, ... Clinical Cancer Research 17 (4), 753-761, 2011 | 66 | 2011 |
| Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats B Velmurugan, RP Singh, A Tyagi, R Agarwal Cancer Prevention Research 1 (5), 376-384, 2008 | 66 | 2008 |
