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Lindsay Comstock
Lindsay Comstock
AssociateProfessor of Chemistry, Wake Forest University
Verified email at wfu.edu
Title
Cited by
Cited by
Year
Conversion of DNA methyltransferases into azidonucleosidyl transferases via synthetic cofactors
LR Comstock, SR Rajski
Nucleic acids research 33 (5), 1644-1652, 2005
792005
Conversion of Aryl Azides to O-Alkyl Imidates via Modified Staudinger Ligation
JA Restituyo, LR Comstock, SG Petersen, T Stringfellow, SR Rajski
Organic Letters 5 (23), 4357-4360, 2003
592003
Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3
A Kasamatsu, M Nakao, BC Smith, LR Comstock, T Ono, J Kato, JM Denu, ...
Journal of Biological Chemistry 286 (24), 21110-21117, 2011
492011
Methyltransferase-directed DNA strand scission
LR Comstock, SR Rajski
Journal of the American Chemical Society 127 (41), 14136-14137, 2005
472005
Synthesis and biochemical evaluation of O-acetyl-ADP-ribose and N-acetyl analogs
LR Comstock, JM Denu
Organic & Biomolecular Chemistry 5 (19), 3087-3091, 2007
292007
Fluorescent DNA Labeling by N‐Mustard Analogues of S‐Adenosyl‐L‐Methionine
Y Du, CE Hendrick, KS Frye, LR Comstock
ChemBioChem 13 (15), 2225-2233, 2012
282012
N-mustard analogs of S-adenosyl-L-methionine as biochemical probes of protein arginine methylation
SJH Bergman, LR Comstock
Bioorganic & medicinal chemistry 23 (15), 5050-5055, 2015
272015
Synthesis of an Azide-Bearing N-Mustard Analogue of S-Adenosyl-l-methionine
V Mai, LR Comstock
The Journal of Organic Chemistry 76 (24), 10319-10324, 2011
252011
Efficient synthesis of azide-bearing cofactor mimics
LR Comstock, SR Rajski
The Journal of Organic Chemistry 69 (4), 1425-1428, 2004
232004
Expeditious synthesis of aziridine-based cofactor mimics
LR Comstock, SR Rajski
Tetrahedron 58 (30), 6019-6026, 2002
232002
Synthesis and evaluation of N6-substituted azide- and alkyne-bearing N-mustard analogs of S-adenosyl-l-methionine
M Ramadan, NK Bremner-Hay, SA Carlson, LR Comstock
Tetrahedron 70 (34), 5291-5297, 2014
202014
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
ZT Laughlin, S Nandi, D Dey, N Zelinskaya, MA Witek, P Srinivas, ...
Proceedings of the National Academy of Sciences 119 (14), e2120352119, 2022
102022
Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
SR Rajski, LR Comstock, RL Weller
US Patent 7,465,544, 2008
92008
Protein Arginine Methyltransferase 1‐Dependent Labeling and Isolation of Histone H4 through N‐Mustard Analogues of S‐Adenosyl‐l‐methionine
SJ Hymbaugh, LM Pecor, CM Tracy, LR Comstock
ChemBioChem 20 (3), 379-384, 2019
72019
O-acetyl-ADP-ribose non-hydrolyzable analogs
JM Denu, LR Comstock
US Patent App. 11/728,503, 2007
42007
tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
SE Strassler, IE Bowles, A Krishnamohan, H Kim, CB Edgington, ...
Journal of Biological Chemistry 299 (12), 2023
22023
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC
P Srinivas, M Nosrati, N Zelinskaya, D Dey, LR Comstock, CM Dunham, ...
Proceedings of the National Academy of Sciences 120 (25), e2304128120, 2023
22023
Evaluation of N‐Mustard Analogues of S‐Adenosyl‐L‐methionine with Eukaryotic DNA Methyltransferase 1
N Sirasunthorn, A Jailwala, A Gerber, LR Comstock
ChemistrySelect 4 (35), 10525-10531, 2019
22019
Sequence-specific DNA strand scission: evaluation of a methyltransferase-dependent chemoselective ligation
LR Comstock
The University of Wisconsin-Madison, 2005
12005
Modification of cytosine-targeted DNA using novel N-mustard analogs of S-Adenosyl-L-Methionine as DNA methylation probes
N Sirasunthorn, L Comstock, A Gerber
Abstracts of Papers of the American Chemical Society 256, 2018
2018
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