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GB Corcoran
GB Corcoran
Professor, Pharmaceutical Sciences, Wayne State University
Verified email at wayne.edu
Title
Cited by
Cited by
Year
Mechanism of Action of N-Acetylcysteine in the Protection Against the Hepatotoxicity of Acetaminophen in Rats In Vivo
BH Lauterburg, GB Corcoran, JR Mitchell
The Journal of clinical investigation 71 (4), 980-991, 1983
4561983
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine
GB Corcoran, JR Mitchell, YN Vaishnav, EC Horning
Molecular pharmacology 18 (3), 536-542, 1980
3611980
Apoptosis: molecular control point in toxicity
GB Corcoran, L Fix, DP Jones, MT Moslen, P Nicotera, FA Oberhammer, ...
Toxicology and applied pharmacology 128 (2), 169-181, 1994
3361994
Predicting creatinine clearance and renal drug clearance in obese patients from estimated fat-free body mass
DE Salazar, GB Corcoran
The American journal of medicine 84 (6), 1053-1060, 1988
3141988
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat
SD Nelson, JR Mitchell, JA Timbrell, WR Snodgrass, GB Corcoran III
Science 193 (4256), 901-903, 1976
2881976
Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: studies with N-acetyl-D-cysteine in mice.
GB Corcoran, BK Wong
Journal of Pharmacology and Experimental Therapeutics 238 (1), 54-61, 1986
2611986
Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen1
SD Ray, LM Kamendulis, MW Gurule, RD Yorkin, GB Corcoran
The FASEB journal 7 (3), 453-463, 1993
2581993
Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice.
GB Corcoran, WJ Racz, CV Smith, JR Mitchell
Journal of Pharmacology and Experimental Therapeutics 232 (3), 864-872, 1985
2211985
Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver
N Patel, C Joseph, GB Corcoran, SD Ray
Toxicology and applied pharmacology 245 (2), 143-152, 2010
2082010
Resveratrol-induced apoptotic death in human U251 glioma cells
H Jiang, L Zhang, J Kuo, K Kuo, SC Gautam, L Groc, AI Rodriguez, ...
Molecular cancer therapeutics 4 (4), 554-561, 2005
1912005
Induction of cytochrome P450IIE1 in the obese overfed rat.
JL Raucy, JM Lasker, JC Kraner, DE Salazar, CS Lieber, GB Corcoran
Molecular pharmacology 39 (3), 275-280, 1991
1891991
Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca2+-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death
W Shen, LM Kamendulis, SD Ray, GB Corcoran
Toxicology and applied pharmacology 112 (1), 32-40, 1992
1561992
Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury
SD Ray, CL Sorge, JL Raucy, GB Corcoran
Toxicology and applied pharmacology 106 (2), 346-351, 1990
1501990
Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: correlation of nuclear Ca2+ accumulation and early DNA fragmentation with cell death
W Shen, LM Kamendulis, SD Ray, GB Corcoran
Toxicology and applied pharmacology 111 (2), 242-254, 1991
1171991
Effects of N-acetylcysteine on the disposition and metabolism of acetaminophen in mice.
GB Corcoran, EL Todd, WJ Racz, H Hughes, CV Smith, JR Mitchell
Journal of Pharmacology and Experimental Therapeutics 232 (3), 857-863, 1985
1041985
The role of the nucleus and other compartments in toxic cell death produced by alkylating hepatotoxicants
GB Corcoran, SD Ray
Toxicology and applied pharmacology 113 (2), 167-183, 1992
811992
Ca (++)-activated DNA fragmentation and dimethylnitrosamine-induced hepatic necrosis: effects of Ca (++)-endonuclease and poly (ADP-ribose) polymerase inhibitors in mice.
SD Ray, CL Sorge, LM Kamendulis, GB Corcoran
Journal of Pharmacology and Experimental Therapeutics 263 (1), 387-394, 1992
781992
Pain sensitivity in dietary-induced obese rats
I Ramzan, BK Wong, GB Corcoran
Physiology & behavior 54 (3), 433-435, 1993
701993
Obesity as a risk factor in drug-induced organ injury: increased liver and kidney damage by acetaminophen in the obese overfed rat.
GB Corcoran, BK Wong
Journal of Pharmacology and Experimental Therapeutics 241 (3), 921-927, 1987
661987
DMBA-induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: relation of cell death to target cell intracellular calcium and DNA damage
SW Burchiel, PD De Ann, SD Ray, MM Archuleta, JP Thilsted, ...
Toxicology and applied pharmacology 113 (1), 126-132, 1992
581992
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