Mechanism of Action of N-Acetylcysteine in the Protection Against the Hepatotoxicity of Acetaminophen in Rats In Vivo BH Lauterburg, GB Corcoran, JR Mitchell The Journal of clinical investigation 71 (4), 980-991, 1983 | 456 | 1983 |
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine GB Corcoran, JR Mitchell, YN Vaishnav, EC Horning Molecular pharmacology 18 (3), 536-542, 1980 | 361 | 1980 |
Apoptosis: molecular control point in toxicity GB Corcoran, L Fix, DP Jones, MT Moslen, P Nicotera, FA Oberhammer, ... Toxicology and applied pharmacology 128 (2), 169-181, 1994 | 336 | 1994 |
Predicting creatinine clearance and renal drug clearance in obese patients from estimated fat-free body mass DE Salazar, GB Corcoran The American journal of medicine 84 (6), 1053-1060, 1988 | 314 | 1988 |
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat SD Nelson, JR Mitchell, JA Timbrell, WR Snodgrass, GB Corcoran III Science 193 (4256), 901-903, 1976 | 288 | 1976 |
Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: studies with N-acetyl-D-cysteine in mice. GB Corcoran, BK Wong Journal of Pharmacology and Experimental Therapeutics 238 (1), 54-61, 1986 | 261 | 1986 |
Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen1 SD Ray, LM Kamendulis, MW Gurule, RD Yorkin, GB Corcoran The FASEB journal 7 (3), 453-463, 1993 | 258 | 1993 |
Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice. GB Corcoran, WJ Racz, CV Smith, JR Mitchell Journal of Pharmacology and Experimental Therapeutics 232 (3), 864-872, 1985 | 221 | 1985 |
Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver N Patel, C Joseph, GB Corcoran, SD Ray Toxicology and applied pharmacology 245 (2), 143-152, 2010 | 208 | 2010 |
Resveratrol-induced apoptotic death in human U251 glioma cells H Jiang, L Zhang, J Kuo, K Kuo, SC Gautam, L Groc, AI Rodriguez, ... Molecular cancer therapeutics 4 (4), 554-561, 2005 | 191 | 2005 |
Induction of cytochrome P450IIE1 in the obese overfed rat. JL Raucy, JM Lasker, JC Kraner, DE Salazar, CS Lieber, GB Corcoran Molecular pharmacology 39 (3), 275-280, 1991 | 189 | 1991 |
Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca2+-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death W Shen, LM Kamendulis, SD Ray, GB Corcoran Toxicology and applied pharmacology 112 (1), 32-40, 1992 | 156 | 1992 |
Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury SD Ray, CL Sorge, JL Raucy, GB Corcoran Toxicology and applied pharmacology 106 (2), 346-351, 1990 | 150 | 1990 |
Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: correlation of nuclear Ca2+ accumulation and early DNA fragmentation with cell death W Shen, LM Kamendulis, SD Ray, GB Corcoran Toxicology and applied pharmacology 111 (2), 242-254, 1991 | 117 | 1991 |
Effects of N-acetylcysteine on the disposition and metabolism of acetaminophen in mice. GB Corcoran, EL Todd, WJ Racz, H Hughes, CV Smith, JR Mitchell Journal of Pharmacology and Experimental Therapeutics 232 (3), 857-863, 1985 | 104 | 1985 |
The role of the nucleus and other compartments in toxic cell death produced by alkylating hepatotoxicants GB Corcoran, SD Ray Toxicology and applied pharmacology 113 (2), 167-183, 1992 | 81 | 1992 |
Ca (++)-activated DNA fragmentation and dimethylnitrosamine-induced hepatic necrosis: effects of Ca (++)-endonuclease and poly (ADP-ribose) polymerase inhibitors in mice. SD Ray, CL Sorge, LM Kamendulis, GB Corcoran Journal of Pharmacology and Experimental Therapeutics 263 (1), 387-394, 1992 | 78 | 1992 |
Pain sensitivity in dietary-induced obese rats I Ramzan, BK Wong, GB Corcoran Physiology & behavior 54 (3), 433-435, 1993 | 70 | 1993 |
Obesity as a risk factor in drug-induced organ injury: increased liver and kidney damage by acetaminophen in the obese overfed rat. GB Corcoran, BK Wong Journal of Pharmacology and Experimental Therapeutics 241 (3), 921-927, 1987 | 66 | 1987 |
DMBA-induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: relation of cell death to target cell intracellular calcium and DNA damage SW Burchiel, PD De Ann, SD Ray, MM Archuleta, JP Thilsted, ... Toxicology and applied pharmacology 113 (1), 126-132, 1992 | 58 | 1992 |