Jose L. Medina-Franco
Cited by
Cited by
Shifting from the single to the multitarget paradigm in drug discovery
JL Medina-Franco, MA Giulianotti, GS Welmaker, RA Houghten
Drug discovery today 18 (9-10), 495-501, 2013
Recognizing pitfalls in virtual screening: a critical review
T Scior, A Bender, G Tresadern, JL Medina-Franco, K Martínez-Mayorga, ...
Journal of chemical information and modeling 52 (4), 867-881, 2012
How to recognize and workaround pitfalls in QSAR studies: a critical review
T Scior, JL Medina-Franco, QT Do, K Martínez-Mayorga, JA Yunes Rojas, ...
Current medicinal chemistry 16 (32), 4297-4313, 2009
In silico Methods for Drug Design and Discovery
S Brogi, TC Ramalho, K Kuca, JL Medina-Franco, M Valko
Frontiers in chemistry 8, 612, 2020
Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors
S Castellano, D Kuck, M Viviano, J Yoo, F López-Vallejo, P Conti, ...
Journal of medicinal chemistry 54 (21), 7663-7677, 2011
Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation
D Kuck, N Singh, F Lyko, JL Medina-Franco
Bioorganic & medicinal chemistry 18 (2), 822-829, 2010
Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?
M Cruz-Monteagudo, JL Medina-Franco, Y Pérez-Castillo, O Nicolotti, ...
Drug Discovery Today 19 (8), 1069-1080, 2014
Integrating virtual screening and combinatorial chemistry for accelerated drug discovery
F López-Vallejo, T Caulfield, K Martínez-Mayorga, M A Giulianotti, A Nefzi, ...
Combinatorial Chemistry & High Throughput Screening 14 (6), 475-487, 2011
Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells
D Kuck, T Caulfield, F Lyko, JL Medina-Franco
Molecular cancer therapeutics 9 (11), 3015-3023, 2010
Visualization of the chemical space in drug discovery
JL Medina-Franco, K Martínez-Mayorga, MA Giulianotti, RA Houghten, ...
Current Computer-Aided Drug Design 4 (4), 322-333, 2008
Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository
N Singh, R Guha, MA Giulianotti, C Pinilla, RA Houghten, ...
Journal of chemical information and modeling 49 (4), 1010-1024, 2009
Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: Consensus Activity Cliffs
JL Medina-Franco, K Martínez-Mayorga, A Bender, RM Marín, ...
Journal of chemical information and modeling 49 (2), 477-491, 2009
A critical overview of computational approaches employed for COVID-19 drug discovery
EN Muratov, R Amaro, CH Andrade, N Brown, S Ekins, D Fourches, ...
Chemical Society Reviews 50 (16), 9121-9151, 2021
Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach
JL Medina-Franco, F López-Vallejo, D Kuck, F Lyko
Molecular diversity 15, 293-304, 2011
Expanding the medicinally relevant chemical space with compound libraries
F López-Vallejo, MA Giulianotti, RA Houghten, JL Medina-Franco
Drug discovery today 17 (13-14), 718-726, 2012
A comparative study of flavonoid analogues on streptozotocin–nicotinamide induced diabetic rats: Quercetin as a potential antidiabetic agent acting via 11β-hydroxysteroid …
M Torres-Piedra, R Ortiz-Andrade, R Villalobos-Molina, N Singh, ...
European journal of medicinal chemistry 45 (6), 2606-2612, 2010
Antidiabetic activity of N-(6-substituted-1, 3-benzothiazol-2-yl) benzenesulfonamides
H Moreno-Díaz, R Villalobos-Molina, R Ortiz-Andrade, D Díaz-Coutiño, ...
Bioorganic & Medicinal Chemistry Letters 18 (9), 2871-2877, 2008
Computational drug design methods—current and future perspectives
FD Prieto-Martínez, E López-López, KE Juárez-Mercado, ...
In silico drug design, 19-44, 2019
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches
JJ Ramírez-Espinosa, MY Rios, S López-Martínez, F López-Vallejo, ...
European journal of medicinal chemistry 46 (6), 2243-2251, 2011
Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods
RA Houghten, C Pinilla, MA Giulianotti, JR Appel, CT Dooley, A Nefzi, ...
Journal of combinatorial chemistry 10 (1), 3-19, 2008
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