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Nikhlesh Singh
Nikhlesh Singh
Associate professor, IBio, Wayne State University School of Medicine
Verified email at wayne.edu
Title
Cited by
Cited by
Year
Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies
NK Singh, GN Rao
Progress in lipid research 73, 28-45, 2019
2312019
Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15 (S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
HSK Potula, D Wang, D Van Quyen, NK Singh, V Kundumani-Sridharan, ...
Journal of biological chemistry 284 (45), 31142-31155, 2009
692009
ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation
S Kotla, NK Singh, GN Rao
Redox biology 11, 350-364, 2017
672017
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis
S Kotla, NK Singh, MR Heckle, GJ Tigyi, GN Rao
Science signaling 6 (293), ra83-ra83, 2013
672013
Vascular endothelial tight junctions and barrier function are disrupted by 15 (S)-hydroxyeicosatetraenoic acid partly via protein kinase Cϵ-mediated zona occludens-1 …
R Chattopadhyay, E Dyukova, NK Singh, M Ohba, JA Mobley, GN Rao
Journal of Biological Chemistry 289 (6), 3148-3163, 2014
662014
Inhibition of 1, 2-dimethylhydrazine induced colon genotoxicity in rats by the administration of probiotic curd
A Kumar, NK Singh, PR Sinha
Molecular biology reports 37, 1373-1376, 2010
652010
NFATc1 targets cyclin A in the regulation of vascular smooth muscle cell multiplication during restenosis
M Karpurapu, D Wang, NK Singh, Q Li, GN Rao
Journal of biological chemistry 283 (39), 26577-26590, 2008
552008
Protein Kinase Cθ Via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6Chi Cells Contributes to Atherosclerosis
S Raghavan, NK Singh, S Gali, AM Mani, GN Rao
Circulation 138 (21), 2395-2412, 2018
482018
Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber …
V Kundumani-Sridharan, NK Singh, S Kumar, R Gadepalli, GN Rao
Journal of Biological Chemistry 288 (30), 22150-22162, 2013
452013
15-Lipoxygenase-1-enhanced Src-Janus kinase 2-signal transducer and activator of transcription 3 stimulation and monocyte chemoattractant protein-1 expression require redox …
NK Singh, D Wang, V Kundumani-Sridharan, D Van Quyen, J Niu, ...
Journal of Biological Chemistry 286 (25), 22478-22488, 2011
452011
AP-1 (Fra-1/c-Jun)-mediated induction of expression of matrix metalloproteinase-2 is required for 15 (S)-hydroxyeicosatetraenoic acid-induced angiogenesis
NK Singh, D Van Quyen, V Kundumani-Sridharan, PC Brooks, GN Rao
Journal of biological chemistry 285 (22), 16830-16843, 2010
432010
Protein kinase N1 is a novel substrate of NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood …
NK Singh, V Kundumani-Sridharan, S Kumar, SK Verma, S Kotla, H Mukai, ...
Journal of Biological Chemistry 287 (43), 36291-36304, 2012
422012
The role of inflammation in retinal neurodegeneration and degenerative diseases
G Kaur, NK Singh
International Journal of Molecular Sciences 23 (1), 386, 2021
402021
15 (S)-hydroxyeicosatetraenoic acid–induced angiogenesis requires Src-mediated Egr-1–dependent rapid induction of FGF-2 expression
V Kundumani-Sridharan, J Niu, D Wang, D Van Quyen, Q Zhang, ...
Blood, The Journal of the American Society of Hematology 115 (10), 2105-2116, 2010
402010
Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration
R Gadepalli, S Kotla, MR Heckle, SK Verma, NK Singh, GN Rao
Journal of Biological Chemistry 288 (43), 30815-30831, 2013
382013
New-age vaccine adjuvants, their development, and future perspective
SK Verma, P Mahajan, NK Singh, A Gupta, R Aggarwal, R Rappuoli, ...
Frontiers in Immunology 14, 1043109, 2023
352023
ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15 (S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation
S Kotla, NK Singh, JG Traylor Jr, AW Orr, GN Rao
Free Radical Biology and Medicine 76, 147-162, 2014
322014
Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA2 activation and retinal neovascularization
NK Singh, DE Hansen III, V Kundumani-Sridharan, GN Rao
Blood, The Journal of the American Society of Hematology 121 (10), 1911-1923, 2013
322013
p115 RhoGEF activates the Rac1 GTPase signaling cascade in MCP1 chemokine–induced vascular smooth muscle cell migration and proliferation
NK Singh, J Janjanam, GN Rao
Journal of Biological Chemistry 292 (34), 14080-14091, 2017
312017
Cyclic AMP response element binding protein mediates pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling
NK Singh, S Kotla, R Kumar, GN Rao
EBioMedicine 2 (11), 1767-1784, 2015
282015
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