Modulation of the fecal bile acid profile by gut microbiota in cirrhosis G Kakiyama, WM Pandak, PM Gillevet, PB Hylemon, DM Heuman, ... Journal of hepatology 58 (5), 949-955, 2013 | 753 | 2013 |
Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis JS Bajaj, DM Heuman, PB Hylemon, AJ Sanyal, P Puri, RK Sterling, ... Alimentary pharmacology & therapeutics 39 (10), 1113-1125, 2014 | 319 | 2014 |
Colonic inflammation and secondary bile acids in alcoholic cirrhosis G Kakiyama, PB Hylemon, H Zhou, WM Pandak, DM Heuman, DJ Kang, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (11 …, 2014 | 185 | 2014 |
Bile acid 7α-dehydroxylating gut bacteria secrete antibiotics that inhibit Clostridium difficile: role of secondary bile acids JD Kang, CJ Myers, SC Harris, G Kakiyama, IK Lee, BS Yun, K Matsuzaki, ... Cell chemical biology 26 (1), 27-34. e4, 2019 | 169 | 2019 |
A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: Validation by GC-MS and LC-MS [S] G Kakiyama, A Muto, H Takei, H Nittono, T Murai, T Kurosawa, ... Journal of lipid research 55 (5), 978-990, 2014 | 138 | 2014 |
The acidic pathway of bile acid synthesis: Not just an alternative pathway WM Pandak, G Kakiyama Liver research 3 (2), 88-98, 2019 | 116 | 2019 |
Antibiotic‐associated disruption of microbiota composition and function in cirrhosis is restored by fecal transplant JS Bajaj, G Kakiyama, T Savidge, H Takei, ZA Kassam, A Fagan, ... Hepatology 68 (4), 1549-1558, 2018 | 115 | 2018 |
Continued alcohol misuse in human cirrhosis is associated with an impaired gut–liver axis JS Bajaj, G Kakiyama, D Zhao, H Takei, A Fagan, P Hylemon, H Zhou, ... Alcoholism: Clinical and Experimental Research 41 (11), 1857-1865, 2017 | 108 | 2017 |
The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined … JM Ridlon, S Devendran, JM Alves, H Doden, PG Wolf, GV Pereira, L Ly, ... Gut microbes 11 (3), 381-404, 2020 | 90 | 2020 |
Rifaximin exerts beneficial effects independent of its ability to alter microbiota composition DJ Kang, G Kakiyama, NS Betrapally, J Herzog, H Nittono, PB Hylemon, ... Clinical and translational gastroenterology 7 (8), e187, 2016 | 90 | 2016 |
Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells Q Bai, L Xu, G Kakiyama, MA Runge-Morris, PB Hylemon, L Yin, ... Atherosclerosis 214 (2), 350-356, 2011 | 82 | 2011 |
Alterations in gut microbial function following liver transplant JS Bajaj, G Kakiyama, IJ Cox, H Nittono, H Takei, M White, A Fagan, ... Liver Transplantation 24 (6), 752-761, 2018 | 63 | 2018 |
Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis JS Bajaj, N Salzman, C Acharya, H Takei, G Kakiyama, A Fagan, ... JCI insight 4 (24), 2019 | 61 | 2019 |
LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine: 3β-Sulfooxy-12α-hydroxy-5β-cholanoic acid is an abundant nonamidated sulfate T Goto, KT Myint, K Sato, O Wada, G Kakiyama, T Iida, T Hishinuma, ... Journal of Chromatography B 846 (1-2), 69-77, 2007 | 61 | 2007 |
Chemical synthesis of the 3-sulfooxy-7-N-acetylglucosaminyl-24-amidated conjugates of 3β, 7β-dihydroxy-5-cholen-24-oic acid, and related compounds: Unusual, major metabolites … T Iida, G Kakiyama, Y Hibiya, S Miyata, T Inoue, K Ohno, T Goto, N Mano, ... Steroids 71 (1), 18-29, 2006 | 54 | 2006 |
Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein–1c signaling pathway and reduces serum and hepatic … Q Bai, X Zhang, L Xu, G Kakiyama, D Heuman, A Sanyal, WM Pandak, ... Metabolism 61 (6), 836-845, 2012 | 50 | 2012 |
LC/ESI-MS/MS analysis of urinary 3β-sulfooxy-7β-N-acetylglucosaminyl-5-cholen-24-oic acid and its amides: New biomarkers for the detection of Niemann–Pick type C disease M Maekawa, Y Misawa, A Sotoura, H Yamaguchi, M Togawa, K Ohno, ... Steroids 78 (10), 967-972, 2013 | 48 | 2013 |
Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine J Wen, GP Mercado, A Volland, HL Doden, CR Lickwar, T Crooks, ... Science advances 7 (30), eabg1371, 2021 | 44 | 2021 |
Gut microbial composition can differentially regulate bile acid synthesis in humanized mice DJ Kang, PB Hylemon, PM Gillevet, RB Sartor, NS Betrapally, ... Hepatology communications 1 (1), 61-70, 2017 | 41 | 2017 |
Liver-Specific Cholesteryl Ester Hydrolase Deficiency Attenuates Sterol Elimination in the Feces and Increases Atherosclerosis in Ldlr−/− Mice J Bie, J Wang, KE Marqueen, R Osborne, G Kakiyama, W Korzun, ... Arteriosclerosis, thrombosis, and vascular biology 33 (8), 1795-1802, 2013 | 39 | 2013 |