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Ali Nakhi
Ali Nakhi
Scientist, Southern Research, Birmingham, AL, USA
Verified email at southernresearch.org
Title
Cited by
Cited by
Year
Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells
S Kalle AM, Mallika A, Badiger J, Alinakhi, Talukdar P
Biochem Biophys Res Commun 401 (1), 13-19, 2010
992010
A new route to indoles via in situ desilylation–Sonogashira strategy: identification of novel small molecules as potential anti-tuberculosis agents
A Nakhi, B Prasad, U Reddy, RM Rao, S Sandra, R Kapavarapu, ...
MedChemComm 2 (10), 1006-1010, 2011
492011
AlCl 3-mediated hydroarylation–heteroarylation in a single pot: a direct access to densely functionalized olefins of pharmacological interest
A Nakhi, S Archana, GPK Seerapu, KS Chennubhotla, KL Kumar, ...
Chemical communications 49 (56), 6268-6270, 2013
442013
A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53
A Ghosh, A Sengupta, GPK Seerapu, A Nakhi, EVVS Ramarao, N Bung, ...
Biochemical and biophysical research communications 488 (3), 562-569, 2017
412017
Thieno [3, 2-c] pyran-4-one based novel small molecules: Their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents
A Nakhi, R Adepu, D Rambabu, R Kishore, GR Vanaja, AM Kalle, M Pal
Bioorganic & medicinal chemistry letters 22 (13), 4418-4427, 2012
402012
Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2
S Shahinshavali, KA Hossain, AVDN Kumar, AG Reddy, D Kolli, A Nakhi, ...
Tetrahedron letters 61 (40), 152336, 2020
362020
Amberlite IR-120H catalyzed MCR: design, synthesis and crystal structure analysis of 1, 8-dioxodecahydroacridines as potential inhibitors of sirtuins
A Nakhi, P Srinivas, MS Rahman, R Kishore, GPK Seerapu, KL Kumar, ...
Bioorganic & medicinal chemistry letters 23 (6), 1828-1833, 2013
362013
Sequential coupling/desilylation–coupling/cyclization in a single pot under Pd/C–Cu catalysis: Synthesis of 2-(hetero) aryl indoles
RM Rao, UR Ch, N Mulakayala, M Alvala, MK Arunasree, RR Poondra, ...
Organic & Biomolecular Chemistry 9 (10), 3808-3816, 2011
362011
Pyrrolo [2, 3-b] quinoxalines as inhibitors of firefly luciferase: Their Cu-mediated synthesis and evaluation as false positives in a reporter gene assay
A Nakhi, MS Rahman, R Kishore, CLT Meda, GS Deora, KVL Parsa, ...
Bioorganic & medicinal chemistry letters 22 (20), 6433-6441, 2012
322012
Transition metal free hydrolysis/cyclization strategy in a single pot: synthesis of fused furo N-heterocycles of pharmacological interest
A Nakhi, MS Rahman, GPK Seerapu, RK Banote, KL Kumar, P Kulkarni, ...
Organic & Biomolecular Chemistry 11 (30), 4930-4934, 2013
292013
Construction and functionalization of pyranone ring fused with pyran moiety: Design and synthesis of novel pyrano [4, 3-b] pyran-5 (4H)-ones as potential inhibitors of sirtuins
A Nakhi, MS Rahman, S Archana, R Kishore, GPK Seerapu, KL Kumar, ...
Bioorganic & medicinal chemistry letters 23 (14), 4195-4205, 2013
272013
7-Methylation of chenodeoxycholic acid derivatives yields a substantial increase in TGR5 receptor potency
A Nakhi, CM McDermott, KL Stoltz, K John, JE Hawkinson, EA Ambrose, ...
Journal of medicinal chemistry 62 (14), 6824-6830, 2019
222019
NaSH in the construction of thiophene ring fused with N-heterocycles: A rapid and inexpensive synthesis of novel small molecules as potential inducers of apoptosis
SK Kolli, A Nakhi, R Medishetti, S Yellanki, P Kulkarni, RR Raju, M Pal
Bioorganic & Medicinal Chemistry Letters 24 (18), 4460-4465, 2014
212014
Structural modifications that increase gut restriction of bile acid derivatives
A Nakhi, HL Wong, M Weldy, A Khoruts, MJ Sadowsky, PI Dosa
RSC Medicinal Chemistry 12 (3), 394-405, 2021
72021
Ligand-free Pd-catalyzed C–N cross-coupling/cyclization strategy: An unprecedented access to 1-thienyl pyrroloquinoxalines for the new approach towards apoptosis
SK Kolli, A Nakhi, S Archana, M Saridena, GS Deora, S Yellanki, ...
European Journal of Medicinal Chemistry 86, 270-278, 2014
72014
A metal catalyst-free and one-pot synthesis of (3, 4-dihydro-2 H-benzo [b][1, 4] oxazin-2-yl) methanol derivatives in water
SN Singh, S Jayaprakash, KV Reddy, A Nakhi, M Pal
RSC advances 5 (103), 84889-84893, 2015
52015
Divalent nucleobase compounds and uses therefor
SA Thadke, A Nakhi, JDR Perera
US Patent 11,603,369, 2023
32023
Mitochondria‐targeted metformin (mitomet) inhibits lung cancer in cellular models and in mice by enhancing the generation of reactive oxygen species
M Shameem, AJ Bagherpoor, A Nakhi, P Dosa, G Georg, F Kassie
Molecular Carcinogenesis 62 (11), 1619-1629, 2023
12023
Modified Nucleobases with Uniform H-Bonding Interactions, Homo-and Hetero-Basepair Bias, and Mismatch Discrimination
SA Thadke, AY Shaikh, WC Hsieh, A Nakhi, JD Perera
US Patent App. 16/972,873, 2021
2021
2. Modified Nucleobases with Uniform H-Bonding Interactions, Homo- and Hetero-Basepair Bias, and Mismatch Discrimination.
D Ly, Hao & Thadke, Shivaji, Ashif Shaik, Wei-Che Hsieh, Nakhi, Ali & Perera
US Patent App. PCT/US2019/036,017, 2019
2019
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