Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells BW Carey, LWS Finley, JR Cross, CD Allis, CB Thompson Nature 518 (7539), 413-416, 2015 | 957 | 2015 |
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization LWS Finley, A Carracedo, J Lee, A Souza, A Egia, J Zhang, ... Cancer cell 19 (3), 416-428, 2011 | 926 | 2011 |
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling E Verdin, MD Hirschey, LWS Finley, MC Haigis Trends in biochemical sciences 35 (12), 669-675, 2010 | 730 | 2010 |
SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism SM Jeong, C Xiao, LWS Finley, T Lahusen, AL Souza, K Pierce, YH Li, ... Cancer cell 23 (4), 450-463, 2013 | 497 | 2013 |
Hypoxia induces production of L-2-hydroxyglutarate AM Intlekofer, RG Dematteo, S Venneti, LWS Finley, C Lu, AR Judkins, ... Cell metabolism 22 (2), 304-311, 2015 | 494 | 2015 |
Serine catabolism regulates mitochondrial redox control during hypoxia J Ye, J Fan, S Venneti, YW Wan, BR Pawel, J Zhang, LWS Finley, C Lu, ... Cancer discovery 4 (12), 1406-1417, 2014 | 457 | 2014 |
Adrenergic nerves activate an angio-metabolic switch in prostate cancer AH Zahalka, A Arnal-Estapé, M Maryanovich, F Nakahara, CD Cruz, ... Science 358 (6361), 321-326, 2017 | 426 | 2017 |
Short-term calorie restriction enhances skeletal muscle stem cell function M Cerletti, YC Jang, LWS Finley, MC Haigis, AJ Wagers Cell stem cell 10 (5), 515-519, 2012 | 422 | 2012 |
Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity LWS Finley, W Haas, V Desquiret-Dumas, DC Wallace, V Procaccio, ... PloS one 6 (8), e23295, 2011 | 420 | 2011 |
A metabolic prosurvival role for PML in breast cancer A Carracedo, D Weiss, AK Leliaert, M Bhasin, VCJ De Boer, G Laurent, ... The Journal of clinical investigation 122 (9), 3088-3100, 2012 | 288 | 2012 |
Metabolic signatures of cancer cells and stem cells AM Intlekofer, LWS Finley Nature metabolism 1 (2), 177-188, 2019 | 285 | 2019 |
α-Ketoglutarate links p53 to cell fate during tumour suppression JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen, ... Nature 573 (7775), 595-599, 2019 | 250 | 2019 |
The coordination of nuclear and mitochondrial communication during aging and calorie restriction LWS Finley, MC Haigis Ageing research reviews 8 (3), 173-188, 2009 | 243 | 2009 |
Acetylation-dependent regulation of Skp2 function H Inuzuka, D Gao, LWS Finley, W Yang, L Wan, H Fukushima, YR Chin, ... Cell 150 (1), 179-193, 2012 | 228 | 2012 |
SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis MC Haigis, CX Deng, LWS Finley, HS Kim, D Gius Cancer research 72 (10), 2468-2472, 2012 | 214 | 2012 |
Metabolic regulation of chromatin modifications and gene expression JM Schvartzman, CB Thompson, LWS Finley Journal of Cell Biology 217 (7), 2247-2259, 2018 | 202 | 2018 |
A non-canonical tricarboxylic acid cycle underlies cellular identity PK Arnold, BT Jackson, KI Paras, JS Brunner, ML Hart, OJ Newsom, ... Nature 603 (7901), 477-481, 2022 | 175 | 2022 |
Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition JJ Harding, MA Lowery, AH Shih, JM Schvartzman, S Hou, C Famulare, ... Cancer Discovery 8 (12), 1540-1547, 2018 | 175 | 2018 |
Regulation and function of the mammalian tricarboxylic acid cycle PK Arnold, LWS Finley Journal of Biological Chemistry 299 (2), 2023 | 169 | 2023 |
PHD3 loss in cancer enables metabolic reliance on fatty acid oxidation via deactivation of ACC2 NJ German, H Yoon, RZ Yusuf, JP Murphy, LWS Finley, G Laurent, ... Molecular cell 63 (6), 1006-1020, 2016 | 161 | 2016 |