| Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 3065 | 2009 |
| A next generation connectivity map: L1000 platform and the first 1,000,000 profiles A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ... Cell 171 (6), 1437-1452. e17, 2017 | 2541 | 2017 |
| The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors LLC Marotta, V Almendro, A Marusyk, M Shipitsin, J Schemme, SR Walker, ... The Journal of clinical investigation 121 (7), 2723-2735, 2011 | 976 | 2011 |
| CDK8 is a colorectal cancer oncogene that regulates β-catenin activity R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ... Nature 455 (7212), 547-551, 2008 | 793 | 2008 |
| Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy J Barretina, BS Taylor, S Banerji, AH Ramos, M Lagos-Quintana, ... Nature genetics 42 (8), 715-721, 2010 | 786 | 2010 |
| A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection SD Shapira, I Gat-Viks, BOV Shum, A Dricot, MM de Grace, L Wu, ... Cell 139 (7), 1255-1267, 2009 | 734 | 2009 |
| Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells C Scholl, S Fröhling, IF Dunn, AC Schinzel, DA Barbie, SY Kim, SJ Silver, ... Cell 137 (5), 821-834, 2009 | 616 | 2009 |
| AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ... Cancer cell 16 (1), 21-32, 2009 | 615 | 2009 |
| Project DRIVE: a compendium of cancer dependencies and synthetic lethal relationships uncovered by large-scale, deep RNAi screening ER McDonald, A De Weck, MR Schlabach, E Billy, KJ Mavrakis, ... Cell 170 (3), 577-592. e10, 2017 | 597 | 2017 |
| A public genome-scale lentiviral expression library of human ORFs X Yang, JS Boehm, X Yang, K Salehi-Ashtiani, T Hao, Y Shen, R Lubonja, ... Nature methods 8 (8), 659-661, 2011 | 591 | 2011 |
| Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning TR Jones, AE Carpenter, MR Lamprecht, J Moffat, SJ Silver, JK Grenier, ... Proceedings of the National Academy of Sciences 106 (6), 1826-1831, 2009 | 446 | 2009 |
| An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia B Knoechel, JE Roderick, KE Williamson, J Zhu, JG Lohr, MJ Cotton, ... Nature genetics 46 (4), 364-370, 2014 | 383 | 2014 |
| Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays MM Kulkarni, M Booker, SJ Silver, A Friedman, P Hong, N Perrimon, ... Nature methods 3 (10), 833-838, 2006 | 333 | 2006 |
| The transcription factor Eyes absent is a protein tyrosine phosphatase TL Tootle, SJ Silver, EL Davies, V Newman, RR Latek, IA Mills, ... Nature 426 (6964), 299-302, 2003 | 319 | 2003 |
| Signaling circuitries in development: insights from the retinal determination gene network SJ Silver, I Rebay Oxford University Press for The Company of Biologists Limited 132 (1), 3-13, 2005 | 227 | 2005 |
| Proteomic and genetic approaches identify Syk as an AML target CK Hahn, JE Berchuck, KN Ross, RM Kakoza, K Clauser, AC Schinzel, ... Cancer cell 16 (4), 281-294, 2009 | 183 | 2009 |
| ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state Y Chudnovsky, D Kim, S Zheng, WA Whyte, M Bansal, MA Bray, S Gopal, ... Cell reports 6 (2), 313-324, 2014 | 164 | 2014 |
| Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ... Cell 150 (3), 575-589, 2012 | 158 | 2012 |
| Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network SJ Silver, EL Davies, L Doyon, I Rebay Molecular and cellular biology 23 (17), 5989-5999, 2003 | 146 | 2003 |
| New vision from Eyes absent: transcription factors as enzymes I Rebay, SJ Silver, TL Tootle TRENDS in Genetics 21 (3), 163-171, 2005 | 114 | 2005 |
Jesse BoehmInstitute Scientist, Cancer Program, Broad InstituteVerified email at broadinstitute.org
