| Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes M Oresic, S Simell, M Sysi-Aho, K Nanto-Salonen, T Seppänen-Laakso, ... The Journal of experimental medicine 205 (13), 2975-2984, 2008 | 406 | 2008 |
| Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression M Hilvo, C Denkert, L Lehtinen, B Müller, S Brockmöller, ... Cancer research 71 (9), 3236-3245, 2011 | 391 | 2011 |
| Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects–a monozygotic twin study KH Pietiläinen, M Sysi-Aho, A Rissanen, T Seppänen-Laakso, ... PloS one 2 (2), e218, 2007 | 382 | 2007 |
| Normalization method for metabolomics data using optimal selection of multiple internal standards M Sysi-Aho, M Katajamaa, L Yetukuri, M Orešič BMC bioinformatics 8 (1), 1-17, 2007 | 289 | 2007 |
| Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol R Laaksonen, K Ekroos, M Sysi-Aho, M Hilvo, T Vihervaara, D Kauhanen, ... European heart journal 37 (25), 1967-1976, 2016 | 244 | 2016 |
| A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle R Laaksonen, M Katajamaa, H Päivä, M Sysi-Aho, L Saarinen, P Junni, ... PloS one 1 (1), e97, 2006 | 221 | 2006 |
| Metabolome in progression to Alzheimer's disease M Orešič, T Hyötyläinen, SK Herukka, M Sysi-Aho, I Mattila, ... Translational psychiatry 1 (12), e57-e57, 2011 | 217 | 2011 |
| Metabolome in schizophrenia and other psychotic disorders: a general population-based study M Orešič, J Tang, T Seppänen-Laakso, I Mattila, SE Saarni, SI Saarni, ... Genome medicine 3 (3), 1-14, 2011 | 129 | 2011 |
| Circulating ceramides predict cardiovascular outcomes in the population-based FINRISK 2002 cohort AS Havulinna, M Sysi-Aho, M Hilvo, D Kauhanen, R Hurme, K Ekroos, ... Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2424-2430, 2016 | 121 | 2016 |
| Spatial snowdrift game with myopic agents M Sysi-Aho, J Saramäki, J Kertész, K Kaski The European Physical Journal B-Condensed Matter and Complex Systems 44 (1 …, 2005 | 107 | 2005 |
| Statistical methods for handling unwanted variation in metabolomics data AMD Livera, M Sysi-Aho, L Jacob, JA Gagnon-Bartsch, S Castillo, ... Analytical chemistry 87 (7), 3606-3615, 2015 | 106 | 2015 |
| Method for diagnosing risk of type 1 diabetes and for preventing onset of type 1 diabetes M Oresic, M Saarela, J Maukonen, M Sysi-Aho US Patent App. 13/695,059, 2013 | 101 | 2013 |
| COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access RM Salek, S Neumann, D Schober, J Hummel, K Billiau, J Kopka, ... Metabolomics 11 (6), 1587-1597, 2015 | 93 | 2015 |
| Metabolic regulation in progression to autoimmune diabetes M Sysi-Aho, A Ermolov, PV Gopalacharyulu, A Tripathi, ... PLoS Comput Biol 7 (10), e1002257, 2011 | 87 | 2011 |
| Bioinformatics and computational methods for lipidomics PS Niemelä, S Castillo, M Sysi-Aho, M Orešič Journal of Chromatography B 877 (26), 2855-2862, 2009 | 84 | 2009 |
| Plasma concentrations of molecular lipid species in relation to coronary plaque characteristics and cardiovascular outcome: Results of the ATHEROREMO-IVUS study JM Cheng, M Suoniemi, I Kardys, T Vihervaara, SPM de Boer, ... Atherosclerosis 243 (2), 560-566, 2015 | 78 | 2015 |
| Effect of probiotic Lactobacillus rhamnosus GG intervention on global serum lipidomic profiles in healthy adults RA Kekkonen, M Sysi-Aho, T Seppänen-Laakso, I Julkunen, H Vapaatalo, ... World Journal of Gastroenterology: WJG 14 (20), 3188, 2008 | 78 | 2008 |
| Gender, contraceptives and individual metabolic predisposition shape a healthy plasma lipidome S Sales, J Graessler, S Ciucci, R Al-Atrib, T Vihervaara, K Schuhmann, ... Scientific reports 6 (1), 1-14, 2016 | 72 | 2016 |
| Self-organization and missing values in SOM and GTM T Vatanen, M Osmala, T Raiko, K Lagus, M Sysi-Aho, M Orešič, T Honkela, ... Neurocomputing 147, 60-70, 2015 | 71 | 2015 |
| Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes M Orešič, P Gopalacharyulu, J Mykkänen, N Lietzen, M Mäkinen, ... Diabetes 62 (9), 3268-3274, 2013 | 71 | 2013 |
Gopal PeddintiSenior Scientist, VTT Technical Research Center of FinlandVerified email at vtt.fi
