Darryl R. Overby
Darryl R. Overby
Professor, Dept. of Bioengineering, Imperial College London
Verified email at
Cited by
Cited by
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels
BD Matthews, DR Overby, R Mannix, DE Ingber
Journal of cell science 119 (3), 508-518, 2006
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins
BD Matthews, CK Thodeti, JD Tytell, A Mammoto, DR Overby, DE Ingber
Integrative Biology 2 (9), 435-442, 2010
The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium
DR Overby, WD Stamer, M Johnson
Experimental eye research 88 (4), 656-670, 2009
Consensus recommendations for trabecular meshwork cell isolation, characterization and culture
KE Keller, SK Bhattacharya, T Borrás, TM Brunner, S Chansangpetch, ...
Experimental eye research 171, 164-173, 2018
Unconventional aqueous humor outflow: a review
M Johnson, JW McLaren, DR Overby
Experimental eye research 158, 94-111, 2017
Reduction of the available area for aqueous humor outflow and increase in meshwork herniations into collector channels following acute IOP elevation in bovine eyes
SA Battista, Z Lu, S Hofmann, T Freddo, DR Overby, H Gong
Investigative ophthalmology & visual science 49 (12), 5346-5352, 2008
eNOS, a pressure-dependent regulator of intraocular pressure
WD Stamer, Y Lei, A Boussommier-Calleja, DR Overby, CR Ethier
Investigative ophthalmology & visual science 52 (13), 9438-9444, 2011
Mechanical properties of individual focal adhesions probed with a magnetic microneedle
BD Matthews, DR Overby, FJ Alenghat, J Karavitis, Y Numaguchi, ...
Biochemical and biophysical research communications 313 (3), 758-764, 2004
Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma
DR Overby, EH Zhou, R Vargas-Pinto, RM Pedrigi, R Fuchshofer, ...
Proceedings of the national Academy of Sciences 111 (38), 13876-13881, 2014
Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction
WD Stamer, ST Braakman, EH Zhou, CR Ethier, JJ Fredberg, DR Overby, ...
Progress in retinal and eye research 44, 86-98, 2015
The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes
Z Lu, DR Overby, PA Scott, TF Freddo, H Gong
Experimental eye research 86 (2), 271-281, 2008
Water content, not stiffness, dominates Brillouin spectroscopy measurements in hydrated materials
PJ Wu, IV Kabakova, JW Ruberti, JM Sherwood, IE Dunlop, C Paterson, ...
Nature methods 15 (8), 561-562, 2018
Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice
DR Overby, J Bertrand, OY Tektas, A Boussommier-Calleja, M Schicht, ...
Investigative ophthalmology & visual science 55 (8), 4922-4933, 2014
α4β1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α4-cytoplasmic domain
R Alon, SW Feigelson, E Manevich, DM Rose, J Schmitz, DR Overby, ...
The Journal of cell biology 171 (6), 1073-1084, 2005
Outflow physiology of the mouse eye: pressure dependence and washout
Y Lei, DR Overby, A Boussommier-Calleja, WD Stamer, CR Ethier
Investigative ophthalmology & visual science 52 (3), 1865-1871, 2011
The mechanism of increasing outflow facility during washout in the bovine eye
D Overby, H Gong, G Qiu, TF Freddo, M Johnson
Investigative ophthalmology & visual science 43 (11), 3455-3464, 2002
Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes
G Li, D Mukherjee, I Navarro, NE Ashpole, JM Sherwood, J Chang, ...
European journal of pharmacology 787, 20-31, 2016
Measurement of Outflow Facility Using iPerfusion
JM Sherwood, E Reina-Torres, JA Bertrand, B Rowe, DR Overby
PloS one 11 (3), e0150694, 2016
A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy
H Gong, J Ruberti, D Overby, M Johnson, TF Freddo
Experimental eye research 75 (3), 347-358, 2002
The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of pilocarpine on outflow facility in mice
DR Overby, J Bertrand, M Schicht, F Paulsen, WD Stamer, ...
Investigative ophthalmology & visual science 55 (6), 3727-3736, 2014
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