A therapeutic approach to pantothenate kinase associated neurodegeneration LK Sharma, C Subramanian, MK Yun, MW Frank, SW White, CO Rock, ... Nature communications 9 (1), 4399, 2018 | 80 | 2018 |
Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide–herboxidiene hybrid analog and related derivatives C Lagisetti, MV Yermolina, LK Sharma, G Palacios, BJ Prigaro, TR Webb ACS chemical biology 9 (3), 643-648, 2014 | 76 | 2014 |
Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel RS Kasinathan, LK Sharma, C Cunningham, TR Webb, RM Greenberg PLoS neglected tropical diseases 8 (10), e3265, 2014 | 65 | 2014 |
Revisiting the role of the immunoproteasome in the activation of the canonical NF-κB pathway ER Jang, NR Lee, S Han, Y Wu, LK Sharma, KC Carmony, J Marks, ... Molecular BioSystems 8 (9), 2295-2302, 2012 | 40 | 2012 |
A selective solvent-free self-condensation of carbonyl compounds utilizing microwave irradiation LK Sharma, KB Kim, GI Elliott Green Chemistry 13 (6), 1546-1549, 2011 | 33 | 2011 |
Allosteric regulation of mammalian pantothenate kinase C Subramanian, MK Yun, J Yao, LK Sharma, RE Lee, SW White, ... Journal of Biological Chemistry 291 (42), 22302-22314, 2016 | 31 | 2016 |
A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases LK Sharma, R Leonardi, W Lin, VA Boyd, A Goktug, AA Shelat, T Chen, ... Journal of Medicinal Chemistry 58 (3), 1563-1568, 2015 | 30 | 2015 |
Near-Infrared Activity-Based Fluorescent Probe for LMP7: A Chemical Proteomics Tool for Immunoproteasome in Living Cells LK Sharma, NR Lee, ER Jang, B Lei, CG Zhan, W Lee, KB Kim Chembiochem: a European journal of chemical biology 13 (13), 1899, 2012 | 21 | 2012 |
A FRET-based approach for identification of proteasome catalytic subunit composition JE Park, Y Wu, KC Carmony, Z Miller, LK Sharma, DM Lee, DY Kim, ... Molecular BioSystems 10 (2), 196-200, 2014 | 16 | 2014 |
Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel LK Sharma, PM Cupit, T Goronga, TR Webb, C Cunningham Bioorganic & medicinal chemistry letters 24 (11), 2469-2472, 2014 | 14 | 2014 |
Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus … H Lee, S Boyle-Vavra, J Ren, JA Jarusiewicz, LK Sharma, DT Hoagland, ... Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 02593-18, 2019 | 13 | 2019 |
The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I AK Mugengana, NA Vita, A Brown Gandt, K Moran, G Agyapong, ... ACS infectious diseases 7 (5), 1044-1058, 2021 | 10 | 2021 |
Elucidating the Catalytic Subunit Composition of Distinct Proteasome Subtypes: A Crosslinking Approach Employing Bifunctional Activity‐Based Probes K Cornish Carmony, LK Sharma, DM Lee, JE Park, W Lee, KB Kim ChemBioChem 16 (2), 284-292, 2015 | 9 | 2015 |
LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators LK Sharma, MK Yun, C Subramanian, R Tangallapally, S Jackowski, ... Bioorganic & medicinal chemistry 52, 116504, 2021 | 3 | 2021 |
Small molecule modulators of pantothenate kinases LK Sharma, RE Lee, CO Rock, S Jackowski, MK Yun, C Subramanian, ... US Patent 10,899,734, 2021 | 2 | 2021 |
Methods of treating disorders associated with castor S Jackowski, CO Rock, RE Lee, LK Sharma, MK Yun, C Subramanian, ... US Patent 11,547,709, 2023 | 1 | 2023 |
Development of novel chemical tools for proteasome biology & a new approach to 1-azaspirocyclic ring system L Kumar University of Kentucky, 2012 | 1 | 2012 |
1′-Ethylsulfanyl-1, 1′-bicyclohexyl-2-one LK Sharma, S Parkin, GI Elliott Acta Crystallographica Section E: Structure Reports Online 66 (4), o932-o932, 2010 | 1 | 2010 |
Methods of treating disorders associated with castor S Jackowski, CO Rock, RE Lee, LK Sharma, MK Yun, C Subramanian, ... US Patent App. 18/076,044, 2023 | | 2023 |
Small molecule modulators of pantothenate kinases LK Sharma, RE Lee, CO Rock, S Jackowski, MK Yun, C Subramanian, ... US Patent App. 17/120,800, 2021 | | 2021 |