Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity RH McMahan, L Golden-Mason, MI Nishimura, BJ McMahon, M Kemper, ... The Journal of clinical investigation 120 (12), 4546-4557, 2010 | 375 | 2010 |
High‐fat and high‐sucrose (western) diet induces steatohepatitis that is dependent on fructokinase T Ishimoto, MA Lanaspa, CJ Rivard, CA Roncal‐Jimenez, DJ Orlicky, ... Hepatology 58 (5), 1632-1643, 2013 | 355 | 2013 |
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease RH McMahan, XX Wang, LL Cheng, T Krisko, M Smith, K El Kasmi, ... Journal of Biological Chemistry 288 (17), 11761-11770, 2013 | 235 | 2013 |
A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection JA Mengshol, L Golden-Mason, T Arikawa, M Smith, T Niki, R McWilliams, ... PloS one 5 (3), e9504, 2010 | 220 | 2010 |
Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines RH McMahan, JA McWilliams, KR Jordan, SW Dow, DB Wilson, ... The Journal of clinical investigation 116 (9), 2543-2551, 2006 | 157 | 2006 |
Galectin-9 functionally impairs natural killer cells in humans and mice L Golden-Mason, RH McMahan, M Strong, R Reisdorph, S Mahaffey, ... Journal of virology 87 (9), 4835-4845, 2013 | 129 | 2013 |
Dietary lipids differentially shape nonalcoholic steatohepatitis progression and the transcriptome of Kupffer cells and infiltrating macrophages B McGettigan, R McMahan, D Orlicky, M Burchill, T Danhorn, P Francis, ... Hepatology 70 (1), 67-83, 2019 | 90 | 2019 |
Mobilizing the low-avidity T cell repertoire to kill tumors RH McMahan, JE Slansky Seminars in cancer biology 17 (4), 317-329, 2007 | 77 | 2007 |
Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions DJ Orlicky, AE Libby, ES Bales, RH McMahan, J Monks, FG La Rosa, ... The Journal of physiology 597 (6), 1565-1584, 2019 | 71 | 2019 |
Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens KR Jordan, RH McMahan, CB Kemmler, JW Kappler, JE Slansky Proceedings of the National Academy of Sciences 107 (10), 4652-4657, 2010 | 70 | 2010 |
Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury C Altmann, A Andres-Hernando, RH McMahan, N Ahuja, Z He, CJ Rivard, ... American Journal of Physiology-Renal Physiology 302 (4), F421-F432, 2012 | 62 | 2012 |
How an alloreactive T-cell receptor achieves peptide and MHC specificity Y Wang, NK Singh, TT Spear, LM Hellman, KH Piepenbrink, ... Proceedings of the National Academy of Sciences 114 (24), E4792-E4801, 2017 | 52 | 2017 |
Free fatty acids differentially downregulate chemokines in liver sinusoidal endothelial cells: insights into non-alcoholic fatty liver disease RH McMahan, CE Porsche, MG Edwards, HR Rosen PLoS One 11 (7), e0159217, 2016 | 48 | 2016 |
Age-related changes in intestinal immunity and the microbiome T Walrath, KU Dyamenahalli, HJ Hulsebus, RL McCullough, JP Idrovo, ... Journal of Leucocyte Biology 109 (6), 1045-1061, 2021 | 47 | 2021 |
Age-dependent tolerance to an endogenous tumor-associated antigen JA McWilliams, RT Sullivan, KR Jordan, RH McMahan, CB Kemmler, ... Vaccine 26 (15), 1863-1873, 2008 | 47 | 2008 |
Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time H Li, AL Hughes, N Bano, S McArdle, S Livingston, H Deubner, ... PloS one 6 (5), e19562, 2011 | 38 | 2011 |
Specificity of regulatory CD4+CD25+ T cells for self‐T cell receptor determinants AC Buenafe, L Tsaknaridis, L Spencer, KS Hicks, RH McMahan, L Watson, ... Journal of neuroscience research 76 (1), 129-140, 2004 | 34 | 2004 |
Sevelamer improves steatohepatitis, inhibits liver and intestinal farnesoid X receptor (FXR), and reverses innate immune dysregulation in a mouse model of non-alcoholic fatty … BM McGettigan, RH McMahan, Y Luo, XX Wang, DJ Orlicky, C Porsche, ... Journal of Biological Chemistry 291 (44), 23058-23067, 2016 | 33 | 2016 |
Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity KR Jordan, RH McMahan, JZ Oh, MR Pipeling, DM Pardoll, RM Kedl, ... The Journal of Immunology 180 (1), 188-197, 2008 | 33 | 2008 |
Oxidized low-density lipoprotein drives dysfunction of the liver lymphatic system MA Burchill, JM Finlon, AR Goldberg, AE Gillen, PA Dahms, RH McMahan, ... Cellular and Molecular Gastroenterology and Hepatology 11 (2), 573-595, 2021 | 32 | 2021 |