Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs R Sharma, V Khristov, A Rising, BS Jha, R Dejene, N Hotaling, Y Li, ... Science translational medicine 11 (475), eaat5580, 2019 | 259 | 2019 |
VEGF regulates local inhibitory complement proteins in the eye and kidney LS Keir, R Firth, L Aponik, D Feitelberg, S Sakimoto, E Aguilar, GI Welsh, ... The Journal of clinical investigation 127 (1), 199, 2017 | 142 | 2017 |
Primary cilium-mediated retinal pigment epithelium maturation is disrupted in ciliopathy patient cells HL May-Simera, Q Wan, BS Jha, J Hartford, V Khristov, R Dejene, ... Cell reports 22 (1), 189-205, 2018 | 127 | 2018 |
In Pursuit of Authenticity: Induced Pluripotent Stem Cell‐Derived Retinal Pigment Epithelium for Clinical Applications KJ Miyagishima, Q Wan, B Corneo, R Sharma, MR Lotfi, NC Boles, F Hua, ... Stem cells translational medicine 5 (11), 1562-1574, 2016 | 99 | 2016 |
Biallelic mutations in MITF cause coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness A George, DJ Zand, RB Hufnagel, R Sharma, YV Sergeev, JM Legare, ... The American Journal of Human Genetics 99 (6), 1388-1394, 2016 | 92 | 2016 |
Production of cloned and transgenic embryos using buffalo (Bubalus bubalis) embryonic stem cell-like cells isolated from in vitro fertilized and cloned blastocysts MSC Aman George, Ruchi Sharma, Karn P Singh, Sudeepta K Panda, Suresh K ... Cellular Reprogramming (Formerly" Cloning and Stem Cells") 13 (3), 263-272, 2011 | 71 | 2011 |
Retinal Pigment Epithelium Replacement Therapy for Age-Related Macular Degeneration: Are We There Yet? R Sharma, D Bose, A Maminishkis, K Bharti Annual Review of Pharmacology and Toxicology 60, 553-572, 2020 | 68 | 2020 |
A multiplex high‐throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell‐derived retinal pigment epithelium M Ferrer, B Corneo, J Davis, Q Wan, KJ Miyagishima, R King, ... Stem cells translational medicine 3 (8), 911-922, 2014 | 65 | 2014 |
Nanofiber Scaffold-Based Tissue-Engineered Retinal Pigment Epithelium to Treat Degenerative Eye Diseases NA Hotaling, V Khristov, Q Wan, R Sharma, BS Jha, M Lotfi, ... Journal of Ocular Pharmacology and Therapeutics 32 (5), 272-285, 2016 | 62 | 2016 |
Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy NJ Schaub, NA Hotaling, P Manescu, S Padi, Q Wan, R Sharma, ... The Journal of clinical investigation, 2019 | 53 | 2019 |
Optimization of Culture Conditions to Support Long-Term Self-Renewal of Buffalo (Bubalus bubalis) Embryonic Stem Cell-Like Cells R Sharma, A George, NM Kamble, KP Singh, MS Chauhan, SK Singla, ... Cellular Reprogramming (Formerly" Cloning and Stem Cells") 13 (6), 539-549, 2011 | 47 | 2011 |
Single-cell–resolution map of human retinal pigment epithelium helps discover subpopulations with differential disease sensitivity D Ortolan, R Sharma, A Volkov, A Maminishkis, NA Hotaling, LA Huryn, ... Proceedings of the National Academy of Sciences 119 (19), e2117553119, 2022 | 42 | 2022 |
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, ... Nature Communications 12 (1), 1-18, 2021 | 36 | 2021 |
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly AG Najim Lahrouchi, I Ratbi, R Schneider, SC Elalaoui, S Moosa, S Bharti, ... Nature communications 10, 2019 | 35 | 2019 |
Effect of scriptaid, a histone deacetylase inhibitor, on the developmental competence of Handmade cloned buffalo (Bubalus bubalis) embryos SK Panda, A George, A Saha, R Sharma, AK Singh, RS Manik, ... Theriogenology 77 (1), 195-200, 2012 | 28 | 2012 |
Longitudinal adaptive optics fluorescence microscopy reveals cellular mosaicism in patients HW Jung, J Liu, AG Tao Liu, MG Smelkinson, S Cohen, R Sharma, ... JCI insight 4 (6), 2019 | 27 | 2019 |
Effect of Cytoplasmic Volume on Developmental Competence of Buffalo (Bubalus bubalis) Embryos Produced Through Hand-Made Cloning SK Panda, A George, AP Saha, R Sharma, RS Manik, MS Chauhan, ... Cellular Reprogramming (Formerly" Cloning and Stem Cells") 13 (3), 257-262, 2011 | 27 | 2011 |
Production of interspecies handmade cloned embryos by nuclear transfer of cattle, goat and rat fibroblasts to buffalo (Bubalus bubalis) oocytes NL Selokar, A George, AP Saha, R Sharma, M Muzaffer, RA Shah, P Palta, ... Animal reproduction science 123 (3-4), 279-282, 2011 | 26 | 2011 |
AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration KJ Miyagishima, R Sharma, M Nimmagadda, K Clore-Gronenborn, ... Communications Biology 4 (1), 1-16, 2021 | 22 | 2021 |
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration MJ Song, R Quinn, E Nguyen, C Hampton, R Sharma, TS Park, C Koster, ... Nature Methods 20 (1), 149-161, 2023 | 21 | 2023 |