| Modifications in an emergency: the role of N1-methylpseudouridine in COVID-19 vaccines KD Nance, JL Meier ACS central science 7 (5), 748-756, 2021 | 268 | 2021 |
| Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping A Sas-Chen, JM Thomas, D Matzov, M Taoka, KD Nance, R Nir, ... Nature 583 (7817), 638-643, 2020 | 193 | 2020 |
| A chemical signature for cytidine acetylation in RNA JM Thomas, CA Briney, KD Nance, JE Lopez, AL Thorpe, SD Fox, ... Journal of the American Chemical Society 140 (40), 12667-12670, 2018 | 75 | 2018 |
| Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia MR Wood, MJ Noetzel, BJ Melancon, MS Poslusney, KD Nance, ... ACS medicinal chemistry letters 8 (2), 233-238, 2017 | 55 | 2017 |
| A Novel M1 PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity JM Rook, JL Bertron, HP Cho, PM Garcia-Barrantes, SP Moran, ... ACS chemical neuroscience 9 (9), 2274-2285, 2018 | 54 | 2018 |
| Diverse Effects on M1 Signaling and Adverse Effect Liability within a Series of M1 Ago-PAMs JM Rook, M Abe, HP Cho, KD Nance, VB Luscombe, JJ Adams, ... ACS chemical neuroscience 8 (4), 866-883, 2017 | 52 | 2017 |
| Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256 MD Grannan, CA Mielnik, SP Moran, RW Gould, J Ball, Z Lu, M Bubser, ... ACS chemical neuroscience 7 (12), 1706-1716, 2016 | 50 | 2016 |
| Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: discovery and SAR of ML354 W Wen, SE Young, MT Duvernay, ML Schulte, KD Nance, BJ Melancon, ... Bioorganic & medicinal chemistry letters 24 (19), 4708-4713, 2014 | 48 | 2014 |
| Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS … LC Morris, KD Nance, PR Gentry, EL Days, CD Weaver, CM Niswender, ... Journal of Medicinal Chemistry 57 (23), 10192-10197, 2014 | 39 | 2014 |
| Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors MJ Uddin, AV Elleman, K Ghebreselasie, CK Daniel, BC Crews, ... ACS Medicinal Chemistry Letters 5 (11), 1254-1258, 2014 | 33 | 2014 |
| Optimization of M4 positive allosteric modulators (PAMs): the discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology BJ Melancon, MR Wood, MJ Noetzel, KD Nance, EM Engelberg, C Han, ... Bioorganic & medicinal chemistry letters 27 (11), 2296-2301, 2017 | 28 | 2017 |
| Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization D Bartee, KD Nance, JL Meier Journal of the American Chemical Society 144 (8), 3487-3496, 2022 | 25 | 2022 |
| Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies KM McGowan, KD Nance, HP Cho, TM Bridges, PJ Conn, CK Jones, ... Bioorganic & medicinal chemistry letters 27 (6), 1356-1359, 2017 | 23 | 2017 |
| A systems chemoproteomic analysis of acyl-CoA/protein interaction networks MJ Levy, DC Montgomery, ME Sardiu, JL Montano, SE Bergholtz, ... Cell chemical biology 27 (3), 322-333. e5, 2020 | 20 | 2020 |
| Remodelin is a cryptic assay interference chemotype that does not inhibit NAT10-dependent cytidine acetylation JH Shrimp, Y Jing, ST Gamage, KM Nelson, J Han, KM Bryson, ... ACS Medicinal Chemistry Letters 12 (6), 887-892, 2020 | 18 | 2020 |
| Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes AR Geanes, HP Cho, KD Nance, KM McGowan, PJ Conn, CK Jones, ... Bioorganic & medicinal chemistry letters 26 (18), 4487-4491, 2016 | 16 | 2016 |
| The discovery of VU0486846: steep SAR from a series of M1 PAMs based on a novel benzomorpholine core JL Bertron, HP Cho, PM Garcia-Barrantes, JD Panarese, JM Salovich, ... Bioorganic & medicinal chemistry letters 28 (12), 2175-2179, 2018 | 14 | 2018 |
| Discovery of a Novel Series of Orally Bioavailable and CNS Penetrant Glucagon-like Peptide-1 Receptor (GLP-1R) Noncompetitive Antagonists Based on a 1, 3-Disubstituted-7-aryl-5 … KD Nance, EL Days, CD Weaver, A Coldren, TD Farmer, HP Cho, ... Journal of Medicinal Chemistry 60 (4), 1611-1616, 2017 | 14 | 2017 |
| Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA KD Nance, ST Gamage, MM Alam, A Yang, MJ Levy, CN Link, L Florens, ... Cell chemical biology 29 (2), 312-320. e7, 2022 | 13 | 2022 |
| Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration JD Panarese, HP Cho, JJ Adams, KD Nance, PM Garcia-Barrantes, ... Bioorganic & medicinal chemistry letters 26 (15), 3822-3825, 2016 | 13 | 2016 |
